In the elderly, many chronic diseases and systemic conditions, medications, and salivary dysfunctions, mostly caused by therapeutic radiation and chemotherapy, are associated with hyposalivation and xerostomia, affecting quality of life. The purpose of this study was to identify and evaluate potential factors associated with xerostomia and/or hyposalivation in a local elderly population. Almost half of the participants had hyposalivation and some reported xerostomia. There was a significant association between hyposalivation and xerostomia. Hyposalivation was most common among women, those taking one or more types of medication simultaneously, those taking antidepressants, and participants with rheumatoid arthritis and depression. There was a tendency for individuals with poorer oral-health-related quality of life to exhibit hyposalivation.