دورية أكاديمية
Vitamin D and Male Fertility: An Updated Review
| العنوان: | Vitamin D and Male Fertility: An Updated Review |
|---|---|
| المؤلفون: | Gianmartin Cito, Andrea Cocci, Elisabetta Micelli, Alejandro Gabutti, Giorgio Ivan Russo, Maria Elisabetta Coccia, Giorgio Franco, Sergio Serni, Marco Carini, Alessandro Natali |
| المصدر: | The World Journal of Men's Health, Vol 38, Iss 2, Pp 164-177 (2020) |
| بيانات النشر: | Korean Society for Sexual Medicine and Andrology, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | male infertility, reproduction, semen quality, vitamin d, Medicine, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | To date, the key role of vitamin D in male reproductive system has been suggested, since the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the testis and spermatozoa. Nevertheless, a general consensus about the role of vitamin D in male fertility is still debated. The aim of this review is to provide an updated systematic revision of the current available literature, discussing the experimental and clinical evidence on the role of vitamin D in the regulation of testis hormone production, seminal parameters and male fertility. The consequences of vitamin D deficiency on serum levels of testicular hormones have been analysed by several observational and interventional studies, with controversial results. Equally, the experimental researches not were able to state a certain relationship between vitamin D status and testis hormone production. Possible bias, including age, body mass index, and baseline vitamin D status justified the differences among studies. As well as concerning the effect of vitamin D on semen parameters, most of the studies agreed in the possibility that vitamin D might have a positive effect on human male fertility potential, particularly through better sperm motility. Regarding pregnancy outcomes, normal level of vitamin D seems to be related to better pregnancies. However, all the previous studies displayed a wide heterogeneity in study design, population, methodology, and cut off values used for the evaluation of vitamin D status. Future studies are needed to better clarify the exact role of vitamin D on hormonal and seminal panel in both fertile and infertile men. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2287-4208 2287-4690 |
| Relation: | https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690 |
| DOI: | 10.5534/wjmh.190057 |
| URL الوصول: | https://doaj.org/article/f18182123f2a4102a757cec2ccc60342 |
| رقم الأكسشن: | edsdoj.f18182123f2a4102a757cec2ccc60342 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22874208 22874690 |
|---|---|
| DOI: | 10.5534/wjmh.190057 |