دورية أكاديمية
Comparison of the Relationship between Thyroid Autoimmune Markers and Polycystic Ovary Syndrome in Women with Hypothyroidism versus Healthy Subjects
| العنوان: | Comparison of the Relationship between Thyroid Autoimmune Markers and Polycystic Ovary Syndrome in Women with Hypothyroidism versus Healthy Subjects |
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| المؤلفون: | A Obaid Jasim, J Hameed Abu-Shana, S Abdul Salam Muneam |
| المصدر: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 26, Pp 0-0 (2024) |
| بيانات النشر: | Babol University of Medical Sciences, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | polycystic ovary syndrome, insulin, homeostasis model assessment of insulin resistance (homa-ir), thyroid autoimmune markers, anti-tpo, anti-tg., Medicine, Medicine (General), R5-920 |
| الوصف: | Background and Objective: Polycystic ovarian syndrome (PCOS) is associated with autoimmune thyroid disease and is thought to be one of the most frequent endocrine diseases in women of reproductive age. This research aims to compare the levels of TSH, LH, Insulin, HOMA-IR, and testosterone in women with polycystic ovary syndrome (PCOS) versus healthy subjects of same age and BMI. Methods: This case control study was conducted among 100 patients who referred to Al-elwyah Teaching Hospital. The samples were selected on the basis of symptoms of hypothyroidism, and fertility problems, and polycystic ovary syndrome in two groups of 50. They were diagnosed by specialized doctors in the hospital. The first group consisted of fifty healthy women, and the second group also consisted of fifty women with polycystic ovary syndrome, reproductive problems, and hypothyroidism. Hormonal analyses were performed using a ready-made kit according to the manufacturer's instructions, Roche Cobas, using an ELISA microplate analyzer. Findings: Mean body mass index, insulin, HOMA-IR, testosterone, anti-TPO, anti-TG, thyroid stimulating hormone, and luteinizing hormone, as well as age group (31-40) were respectively as follows: (35.96±0.34, 23.12±0.31, 6.64±0.07, 98.80±0.75, 7.70±0.10, 10.27±0.30). LH and anti-TG insulin levels were positively correlated with their BMI. There was also an inverse relationship between body mass index and HOMA-IR, and between anti-TG and testosterone. Conclusion: The results of the study showed that in patients with polycystic ovary syndrome, increased risk of thyroid disease is related to increased thyroid autoantibody markers and measured hormones, insulin and HOMA-IR. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Persian |
| تدمد: | 1561-4107 2251-7170 |
| Relation: | http://jbums.org/article-1-11313-en.pdf; https://doaj.org/toc/1561-4107; https://doaj.org/toc/2251-7170 |
| URL الوصول: | https://doaj.org/article/f1ded75d89674ce68423a933d8749a80 |
| رقم الأكسشن: | edsdoj.f1ded75d89674ce68423a933d8749a80 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15614107 22517170 |
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