دورية أكاديمية
Understanding VPAC receptor family peptide binding and selectivity
| العنوان: | Understanding VPAC receptor family peptide binding and selectivity |
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| المؤلفون: | Sarah J. Piper, Giuseppe Deganutti, Jessica Lu, Peishen Zhao, Yi-Lynn Liang, Yao Lu, Madeleine M. Fletcher, Mohammed Akhter Hossain, Arthur Christopoulos, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten |
| المصدر: | Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022) |
| بيانات النشر: | Nature Portfolio, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Science |
| مصطلحات موضوعية: | Science |
| الوصف: | Previously, peptide selectivity in the VPAC receptor family of GPCRs was poorly understood. Here, authors combine cryo-EM and MD data to understand binding and selectivity of VPAC1R and PAC1R peptide agonists that can guide future drug development. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2041-1723 37613979 |
| Relation: | https://doaj.org/toc/2041-1723 |
| DOI: | 10.1038/s41467-022-34629-3 |
| URL الوصول: | https://doaj.org/article/f2ad6a82f21b446eaee66d37613979d6 |
| رقم الأكسشن: | edsdoj.f2ad6a82f21b446eaee66d37613979d6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20411723 37613979 |
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| DOI: | 10.1038/s41467-022-34629-3 |