دورية أكاديمية
Isolation and genetic characterization of a relapsing fever spirochete isolated from Ornithodoros puertoricensis collected in central Panama.
العنوان: | Isolation and genetic characterization of a relapsing fever spirochete isolated from Ornithodoros puertoricensis collected in central Panama. |
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المؤلفون: | Sergio E Bermúdez, Brittany A Armstrong, Lillian Domínguez, Aparna Krishnavajhala, Alexander R Kneubehl, Sarah M Gunter, Adam Replogle, Jeannine M Petersen, Job E Lopez |
المصدر: | PLoS Neglected Tropical Diseases, Vol 15, Iss 8, p e0009642 (2021) |
بيانات النشر: | Public Library of Science (PLoS), 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Arctic medicine. Tropical medicine LCC:Public aspects of medicine |
مصطلحات موضوعية: | Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270 |
الوصف: | Tick-borne relapsing fever (TBRF) spirochetes are likely an overlooked cause of disease in Latin America. In Panama, the pathogens were first reported to cause human disease in the early 1900s. Recent collections of Ornithodoros puertoricensis from human dwellings in Panama prompted our interest to determine whether spirochetes still circulate in the country. Ornithodoros puertoricensis ticks were collected at field sites around the City of Panama. In the laboratory, the ticks were determined to be infected with TBRF spirochetes by transmission to mice, and we report the laboratory isolation and genetic characterization of a species of TBRF spirochete from Panama. Since this was the first isolation of a species of TBRF spirochete from Central America, we propose to designate the bacteria as Borrelia puertoricensis sp. nov. This is consistent with TBRF spirochete species nomenclature from North America that are designated after their tick vector. These findings warrant further investigations to assess the threat B. puertoricensis sp. nov. may impose on human health. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1935-2727 1935-2735 |
Relation: | https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735 |
DOI: | 10.1371/journal.pntd.0009642 |
URL الوصول: | https://doaj.org/article/af310e26220648fda08db10a8133a991 |
رقم الأكسشن: | edsdoj.f310e26220648fda08db10a8133a991 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19352727 19352735 |
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DOI: | 10.1371/journal.pntd.0009642 |