دورية أكاديمية
The discovery and importance of genomic imprinting
| العنوان: | The discovery and importance of genomic imprinting |
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| المؤلفون: | Anne C Ferguson-Smith, Deborah Bourc'his |
| المصدر: | eLife, Vol 7 (2018) |
| بيانات النشر: | eLife Sciences Publications Ltd, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Medicine LCC:Science LCC:Biology (General) |
| مصطلحات موضوعية: | genomic imprinting, epigenetics, DNA methylation, germline, mammalian reproduction, epigenetic inheritance, Medicine, Science, Biology (General), QH301-705.5 |
| الوصف: | The discovery of genomic imprinting by Davor Solter, Azim Surani and co-workers in the mid-1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic control of gene activity and repression, especially during development. It also has shed light on a range of diseases, including both rare genetic disorders and common diseases. This article is being published to celebrate Solter and Surani receiving a 2018 Canada Gairdner International Award "for the discovery of mammalian genomic imprinting that causes parent-of-origin specific gene expression and its consequences for development and disease". |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-084X |
| Relation: | https://elifesciences.org/articles/42368; https://doaj.org/toc/2050-084X |
| DOI: | 10.7554/eLife.42368 |
| URL الوصول: | https://doaj.org/article/f48d97c820094e85bdab6d943460af8f |
| رقم الأكسشن: | edsdoj.f48d97c820094e85bdab6d943460af8f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2050084X |
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| DOI: | 10.7554/eLife.42368 |