دورية أكاديمية
Prognostic and clinical value of circPRKCI expression in diverse human cancers
| العنوان: | Prognostic and clinical value of circPRKCI expression in diverse human cancers |
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| المؤلفون: | Zhongyue Liu, Xiaolei Ren, Zhimin Yang, Lin Mei, Wenyi Li, Chao Tu, Zhihong Li, Rongman Jia, Xiuyuan Hao |
| المصدر: | Chinese Medical Journal, Vol 137, Iss 2, Pp 152-161 (2024) |
| بيانات النشر: | Wolters Kluwer, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Medicine |
| الوصف: | Abstract. Background:. Highly expressed in various human cancers, circular RNA Protein Kinase C Iota (circPRKCI) has been reported to play an important role in cancer development and progression. Herein, we sought to reveal the prognostic and clinical value of circPRKCI expression in diverse human cancers. Methods:. We searched the Pubmed, Web of Science, and the Cochrane Library databases from inception until May 16, 2021. The relationship between circPRKCI expression and cancer patients' survival, including overall survival (OS) and disease-free survival (DFS), was assessed by pooled hazard ratios (HR) with corresponding 95% confidence interval (CI). The correlation between circPRKCI expression and clinical outcomes was evaluated using odds ratios (OR) with corresponding 95% CI. The data were analyzed by STATA software (version 12.0) or Review Manager (RevMan 5.3). Results:. A total of 15 studies with 1109 patients were incorporated into our meta-analysis. The results demonstrated that high circPRKCI expression was significantly related to poor OS (HR = 1.96, 95% CI: 1.61, 2.39, P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0366-6999 2542-5641 00000000 |
| Relation: | http://journals.lww.com/10.1097/CM9.0000000000002844; https://doaj.org/toc/0366-6999; https://doaj.org/toc/2542-5641 |
| DOI: | 10.1097/CM9.0000000000002844 |
| URL الوصول: | https://doaj.org/article/f4cda42ed70b4e41b088953a925bad5b |
| رقم الأكسشن: | edsdoj.f4cda42ed70b4e41b088953a925bad5b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03666999 25425641 00000000 |
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| DOI: | 10.1097/CM9.0000000000002844 |