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LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression

التفاصيل البيبلوغرافية
العنوان: LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression
المؤلفون: Zhen-zhen Chen, Lan Huang, Ya-hong Wu, Wen-jie Zhai, Ping-ping Zhu, Yan-feng Gao
المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
بيانات النشر: Nature Portfolio, 2016.
سنة النشر: 2016
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Liver tumour-initiating cells (TICs) may be responsible for liver cancer initiation and recurrence. In this article, the authors show that a previously unidentified lncRNA, LncSox4, is highly expressed in liver cancer TICs and regulates TIC self-renewal through the Stat3/SOX4 axis.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/ncomms12598
URL الوصول: https://doaj.org/article/af4da882b3d24660a0f557ced5498b6f
رقم الأكسشن: edsdoj.f4da882b3d24660a0f557ced5498b6f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/ncomms12598