دورية أكاديمية
LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression
العنوان: | LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression |
---|---|
المؤلفون: | Zhen-zhen Chen, Lan Huang, Ya-hong Wu, Wen-jie Zhai, Ping-ping Zhu, Yan-feng Gao |
المصدر: | Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
بيانات النشر: | Nature Portfolio, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Science |
مصطلحات موضوعية: | Science |
الوصف: | Liver tumour-initiating cells (TICs) may be responsible for liver cancer initiation and recurrence. In this article, the authors show that a previously unidentified lncRNA, LncSox4, is highly expressed in liver cancer TICs and regulates TIC self-renewal through the Stat3/SOX4 axis. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2041-1723 |
Relation: | https://doaj.org/toc/2041-1723 |
DOI: | 10.1038/ncomms12598 |
URL الوصول: | https://doaj.org/article/af4da882b3d24660a0f557ced5498b6f |
رقم الأكسشن: | edsdoj.f4da882b3d24660a0f557ced5498b6f |
قاعدة البيانات: | Directory of Open Access Journals |
كن أول من يترك تعليقا!