The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis

التفاصيل البيبلوغرافية
العنوان:	The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis
المؤلفون:	Lu Han, Yongxia Wu, Kun Fang, Sean Sweeney, Ulyss K. Roesner, Melodie Parrish, Khushbu Patel, Tom Walter, Julia Piermattei, Anthony Trimboli, Julia Lefler, Cynthia D. Timmers, Xue-Zhong Yu, Victor X. Jin, Michael T. Zimmermann, Angela J. Mathison, Raul Urrutia, Michael C. Ostrowski, Gustavo Leone
المصدر:	Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
بيانات النشر:	Nature Portfolio, 2023.
سنة النشر:	2023
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Cancer-associated fibroblasts (CAFs) are the main component of the stroma in pancreatic cancer, but their tissue of origin remains to be defined. Here the authors perform lineage tracing and single cell RNA sequencing in mice and suggest the splanchnic mesenchyme as the tissue of origin for CAFs.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-022-34464-6
URL الوصول:	https://doaj.org/article/f4eb874301cd413b8b8363efaf0dfe69
رقم الأكسشن:	edsdoj.f4eb874301cd413b8b8363efaf0dfe69
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-022-34464-6