دورية أكاديمية
Optic neuritis associated with seronegative autoimmune encephalitis: a case report
العنوان: | Optic neuritis associated with seronegative autoimmune encephalitis: a case report |
---|---|
المؤلفون: | Hyungseok Hah, Yonghyun Lee, Ho-Won Lee, Ji-Ye Jeon |
المصدر: | Encephalitis, Vol 3, Iss 3, Pp 94-96 (2023) |
بيانات النشر: | Korean Encephalitis and Neuroinflammation Society, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Infectious and parasitic diseases LCC:Neurology. Diseases of the nervous system |
مصطلحات موضوعية: | encephalitis, optic neuritis, status epilepticus, Infectious and parasitic diseases, RC109-216, Neurology. Diseases of the nervous system, RC346-429 |
الوصف: | Optic neuritis is an inflammatory demyelinating disorder that primarily affects the optic nerve and is often associated with multiple sclerosis. While it is rare for optic neuritis to be accompanied by autoimmune encephalitis, it can occur in some cases. A 65-year-old woman with bipolar disorder presented with a progressively altered mentality. Magnetic resonance imaging of the brain showed no definite abnormal findings. Electroencephalography revealed nonconvulsive status epilepticus. Cerebrospinal fluid study and autoimmune and paraneoplastic encephalitis antibodies were negative. The patient was diagnosed with seronegative autoimmune encephalitis and treated with methylprednisolone, intravenous immunoglobulin, and rituximab. Her condition gradually improved except for persistent blindness on the left side. This case highlights the importance of considering autoimmune encephalitis even in the absence of identifiable pathogenic antibodies when clinical manifestations and response to immunotherapy support such a diagnosis. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2765-4559 2734-1461 |
Relation: | http://www.encephalitisjournal.org/upload/pdf/encephalitis-2023-00024.pdf; https://doaj.org/toc/2765-4559; https://doaj.org/toc/2734-1461 |
DOI: | 10.47936/encephalitis.2023.00024 |
URL الوصول: | https://doaj.org/article/df5c076fb61e4880991a8996919cd809 |
رقم الأكسشن: | edsdoj.f5c076fb61e4880991a8996919cd809 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 27654559 27341461 |
---|---|
DOI: | 10.47936/encephalitis.2023.00024 |