دورية أكاديمية
Comparing Serum Levels of Th17 and Treg Cytokines in Women with Unexplained Recurrent Spontaneous Abortion and Fertile Women
العنوان: | Comparing Serum Levels of Th17 and Treg Cytokines in Women with Unexplained Recurrent Spontaneous Abortion and Fertile Women |
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المؤلفون: | Narges Roomandeh, AboTaleb Saremi, Javad Arasteh, Fatemeh Pak, Majid Mirmohammadkhani, Parviz Kokhaei, Ahad Zare |
المصدر: | Iranian Journal of Immunology, Vol 15, Iss 1, Pp 59-67 (2018) |
بيانات النشر: | Shiraz University of Medical Sciences, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Biology (General) |
مصطلحات موضوعية: | Biology (General), QH301-705.5 |
الوصف: | Background: Increased evidences have shown that unexplained recurrent spontaneous abortion (URSA) is associated with inflammatory responses and breakage of immunological autotolerance. Therefore, the balance between Th17 and Treg cells may elucidate the pathophysiology of URSA. Objective: To investigate the serum concentration of regulatory and inflammatory cytokines associated with Treg and Th17 in both normal and URSA females. Methods: Forty-six women with URSA and 28 non-pregnant control women with at least one successful pregnancy were included. Serum was obtained from both groups and stored at -70°C. The serum concentrations of IL-17, IL-21, IL-22, IL-10, and TGF-β were quantitatively determined by ELISA. Results: The levels of IL-17, IL-21, and IL-22 in sera were significantly higher (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1735-1383 1735-367X |
Relation: | https://iji.sums.ac.ir/article_39341_4a1ad39e01adb444c4e3fa0ef878e4fe.pdf; https://doaj.org/toc/1735-1383; https://doaj.org/toc/1735-367X |
URL الوصول: | https://doaj.org/article/ef62b8ad61be42db98d1d81e9c1a2f0a |
رقم الأكسشن: | edsdoj.f62b8ad61be42db98d1d81e9c1a2f0a |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17351383 1735367X |
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