دورية أكاديمية

Comparing Serum Levels of Th17 and Treg Cytokines in Women with Unexplained Recurrent Spontaneous Abortion and Fertile Women

التفاصيل البيبلوغرافية
العنوان: Comparing Serum Levels of Th17 and Treg Cytokines in Women with Unexplained Recurrent Spontaneous Abortion and Fertile Women
المؤلفون: Narges Roomandeh, AboTaleb Saremi, Javad Arasteh, Fatemeh Pak, Majid Mirmohammadkhani, Parviz Kokhaei, Ahad Zare
المصدر: Iranian Journal of Immunology, Vol 15, Iss 1, Pp 59-67 (2018)
بيانات النشر: Shiraz University of Medical Sciences, 2018.
سنة النشر: 2018
المجموعة: LCC:Biology (General)
مصطلحات موضوعية: Biology (General), QH301-705.5
الوصف: Background: Increased evidences have shown that unexplained recurrent spontaneous abortion (URSA) is associated with inflammatory responses and breakage of immunological autotolerance. Therefore, the balance between Th17 and Treg cells may elucidate the pathophysiology of URSA. Objective: To investigate the serum concentration of regulatory and inflammatory cytokines associated with Treg and Th17 in both normal and URSA females. Methods: Forty-six women with URSA and 28 non-pregnant control women with at least one successful pregnancy were included. Serum was obtained from both groups and stored at -70°C. The serum concentrations of IL-17, IL-21, IL-22, IL-10, and TGF-β were quantitatively determined by ELISA. Results: The levels of IL-17, IL-21, and IL-22 in sera were significantly higher (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1735-1383
1735-367X
Relation: https://iji.sums.ac.ir/article_39341_4a1ad39e01adb444c4e3fa0ef878e4fe.pdf; https://doaj.org/toc/1735-1383; https://doaj.org/toc/1735-367X
URL الوصول: https://doaj.org/article/ef62b8ad61be42db98d1d81e9c1a2f0a
رقم الأكسشن: edsdoj.f62b8ad61be42db98d1d81e9c1a2f0a
قاعدة البيانات: Directory of Open Access Journals