دورية أكاديمية
Formulation of Anti-Acne Gel of Moringa oleifera L Ethanolic Extract and Antibacterial Test on Staphylococcus epidermidis
| العنوان: | Formulation of Anti-Acne Gel of Moringa oleifera L Ethanolic Extract and Antibacterial Test on Staphylococcus epidermidis |
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| المؤلفون: | Dian Eka Ermawati, Cahyarani Intan Ramadhani |
| المصدر: | Journal of Food and Pharmaceutical Sciences, Pp 34-44 (2019) |
| بيانات النشر: | LPPT Universitas Gadjah Mada, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Pharmacy and materia medica LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | moringa leaves, hpmc 4000, gel, staphylococcus epidermidis, Pharmacy and materia medica, RS1-441, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | Moringa oleifera L. leaves contain flavonoid, alkaloid, and phenolic compounds which have antibacterial activity. Staphylococcus epidermidis is one of the bacteria that causes acne. The purpose of this study is to compare bacteriostatic ability of the extracts and gel for S. epidermidis bacteria and to get gel formula that can fulfills the physical properties of a good gel. Moringa leaves were extracted with maceration method using ethanol 70% in three days. HPMC 4000 was used as the polymer. Extract was added with variation concentrations of 5, 10, and 15%. Physical evaluation of gel was organoleptic, homogeneity, pH, viscosity, adhesion, and spread tests for 4 weeks. In vitro bacteriostatic activity test with 1% clindamycin gel as positive control and polymer gel as negative control. The result showed that variations concentrations of ethanolic extract of Moringa leaves affected the physical properties of gel including viscosity, pH, adhesion and spreadability. Bacteriostatic activity test of ethanolic extract of Moringa leaf was classified as strong activity, while 15% Moringa leaf ethanol extract gel was classified as moderate activity with average diameter was 9.14 mm. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2089-7200 2339-0948 |
| Relation: | https://jurnal.ugm.ac.id/v3/JFPS/article/view/707; https://doaj.org/toc/2089-7200; https://doaj.org/toc/2339-0948 |
| DOI: | 10.22146/jfps.707 |
| URL الوصول: | https://doaj.org/article/ccf6395a3c614a10afd0b611da6df93f |
| رقم الأكسشن: | edsdoj.f6395a3c614a10afd0b611da6df93f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20897200 23390948 |
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| DOI: | 10.22146/jfps.707 |