دورية أكاديمية

Nomogram prediction model for renal anaemia in IgA nephropathy patients

التفاصيل البيبلوغرافية
العنوان: Nomogram prediction model for renal anaemia in IgA nephropathy patients
المؤلفون: Li Fei, Wei Ri-bao, Wang Yang, Su Ting-yu, Li Ping, Huang Meng-jie, Chen Xiang-mei
المصدر: Open Medicine, Vol 16, Iss 1, Pp 718-727 (2021)
بيانات النشر: De Gruyter, 2021.
سنة النشر: 2021
المجموعة: LCC:Medicine
مصطلحات موضوعية: iga nephropathy, anaemia, chronic kidney disease, nomogram, Medicine
الوصف: In this study, we focused on the influencing factors of renal anaemia in patients with IgA nephropathy and constructed a nomogram model. We divided 462 patients with IgA nephropathy diagnosed by renal biopsy into anaemic and non-anaemic groups. Then, the influencing factors of renal anaemia in patients with IgA nephropathy were analysed by least absolute shrinkage and selection operator (LASSO) regression and multivariable logistic regression, and a nomogram model for predicting renal anaemia was established. Eventually, nine variables were obtained, which are easy to apply clinically. The areas under the receiver operating characteristic (ROC) curve and precision-recall (PR) curve reached 0.835 and 0.676, respectively, and the C-index reached 0.848. The calibration plot showed that the model had good discrimination, accuracy, and diagnostic efficacy. In addition, the C-index of the model following internal validation reached 0.823. Decision curve analysis suggested that the model had a certain degree of clinical significance. This new nomogram model of renal anaemia combines the basic information, laboratory findings, and renal biopsy results of patients with IgA nephropathy, providing important guidance for predicting and clinically intervening in renal anaemia.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2391-5463
Relation: https://doaj.org/toc/2391-5463
DOI: 10.1515/med-2021-0284
URL الوصول: https://doaj.org/article/f68e2650e48f4bc19397bba5ccb5cddb
رقم الأكسشن: edsdoj.f68e2650e48f4bc19397bba5ccb5cddb
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23915463
DOI:10.1515/med-2021-0284