دورية أكاديمية
Micropeptides translated from putative long non-coding RNAs
| العنوان: | Micropeptides translated from putative long non-coding RNAs |
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| المؤلفون: | Li Junhong, Qu Lei, Sang Lingjie, Wu Xinyu, Jiang Anlan, Liu Jian, Lin Aifu |
| المصدر: | Acta Biochimica et Biophysica Sinica, Vol 54, Pp 292-300 (2022) |
| بيانات النشر: | China Science Publishing & Media Ltd., 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Biochemistry LCC:Genetics |
| مصطلحات موضوعية: | long non-coding RNA (lncRNA), small open reading frame (sORF), micropeptide, coding-potential, Biochemistry, QD415-436, Genetics, QH426-470 |
| الوصف: | Long non-coding RNAs (lncRNAs) transcribed in mammals and eukaryotes were thought to have no protein coding capability. However, recent studies have suggested that plenty of lncRNAs are mis-annotated and virtually contain coding sequences which are translated into bona fide functional peptides by ribosomal machinery, and these functional peptides are called micropeptides or small peptides. Here we review the rapidly advancing field of micropeptides translated from putative lncRNAs, describe the strategies for their identification, and elucidate their critical roles in many fundamental biological processes. We also discuss the prospects of research in micropeptides and the potential applications of micropeptides. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1672-9145 83419411 |
| Relation: | https://doaj.org/toc/1672-9145 |
| DOI: | 10.3724/abbs.2022010 |
| URL الوصول: | https://doaj.org/article/af7b8e3638744b1fb834194114eff4cd |
| رقم الأكسشن: | edsdoj.f7b8e3638744b1fb834194114eff4cd |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16729145 83419411 |
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| DOI: | 10.3724/abbs.2022010 |