دورية أكاديمية
Effects of 3% binahong (Anredera cordifolia) leaf extract gel on alveolar bone healing in post-extraction tooth socket wound in Wistar rats (Rattus norvegicus) [version 2; peer review: 1 approved, 2 approved with reservations]
| العنوان: | Effects of 3% binahong (Anredera cordifolia) leaf extract gel on alveolar bone healing in post-extraction tooth socket wound in Wistar rats (Rattus norvegicus) [version 2; peer review: 1 approved, 2 approved with reservations] |
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| المؤلفون: | Olivia Avriyanti Hanafiah, Denny Satria, Diana Sofia Hanafiah, Gostry Aldica Dohude, Livita Livita, Nindha Siti Moudy, Rahma Rahma |
| المصدر: | F1000Research, Vol 10 (2022) |
| بيانات النشر: | F1000 Research Ltd, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Anredera cordifolia, tooth extraction, wound healing, fibroblasts, osteoblasts, osteocytes, eng, Medicine, Science |
| الوصف: | Background: Binahong (Anredera cordifolia (Ten.) STEENIS) is a widely available herbal plant in Indonesia and has been intensely researched for its healing abilities due to its biological activities, but few have studied its capability in accelerating hard tissue healing in post-extraction tooth sockets. The purpose of this study was to analyse the effects of 3% binahong leaf extract gel on alveolar bone healing in post-extraction sockets in Wistar rats. Methods: In this study, 48 male Wistar rats were randomly allocated to twelve groups. After the extraction of the left mandibular incisor, sockets in Group I to IV were given 3% binahong leaf extract gel, group V to VIII were given a control gel, and group IX to XII were given Gengigel® for 14 days. The residual socket volume (RSV) and fibroblast proliferation were observed on the 3rd, 7th, and 14th day post-extraction, while the osteoblast and osteocyte proliferation were observed on the 7th, 14th, and 28th day post-extraction. The RSV data were analysed using repeated measure ANOVA and one-way ANOVA, while the histopathological data were analysed using one-way ANOVA. Results: The results showed that the binahong group had the lowest RSV and the highest fibroblast proliferation compared to the other groups on the 7th day (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2046-1402 |
| Relation: | https://f1000research.com/articles/10-923/v2; https://doaj.org/toc/2046-1402 |
| DOI: | 10.12688/f1000research.72982.2 |
| URL الوصول: | https://doaj.org/article/f7e5514961a04f499455317e3a3542c7 |
| رقم الأكسشن: | edsdoj.f7e5514961a04f499455317e3a3542c7 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20461402 |
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| DOI: | 10.12688/f1000research.72982.2 |