دورية أكاديمية
THE USE OF BACTERIOPHAGES IN THE TREATMENT OF STAPHYLOCOCCAL INFECTION
| العنوان: | THE USE OF BACTERIOPHAGES IN THE TREATMENT OF STAPHYLOCOCCAL INFECTION |
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| المؤلفون: | Dmitri IUNAC, Lucia GALBEN, Alina FERDOHLEB, Elena CIOBANU, Greta BALAN |
| المصدر: | Anthropological Researches and Studies, Vol 14, Pp 302-313 (2024) |
| بيانات النشر: | “Francisc I. Rainer” Anthropology Institute of the Romanian Academy., 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Geography. Anthropology. Recreation LCC:Anthropology |
| مصطلحات موضوعية: | staphylococcal infections, resistance to antibiotics, bacteriophages, phage therapy, Geography. Anthropology. Recreation, Anthropology, GN1-890 |
| الوصف: | Aim of study. The current rate of increase in the number of antimicrobial-resistant infections is poised to become the leading global cause of loss of human life. The limited discovery of new antibiotics necessitates investment in alternative solutions. Bacteriophages, viruses that target bacteria, offer a potent alternative approach to combating bacterial infections. One area of modern microbiology and biotechnology that has garnered significant interest is the study of bacteriophages, owing to their potential practical application in various branches of medicine. Material and methods. This study conducted a comprehensive synthesis of specialized reference sources from international open-access databases, examining the impact of bacteriophage therapy on staphylococcal infections and antimicrobial resistance. Results. The synthesis is based on studies in human clinical trials, including randomized clinical trials, based on data from recent years. Multiple successful cases regarding the use of phages in the treatment of human infections have been reported. The studies conducted provide evidence that the development of phage therapy is a promising alternative for combating bacterial resistance to antibiotics. The effective action of antistaphylococcal phage cocktails against the most common strains has been demonstrated. The mechanisms underlying the phage-antibiotic synergy effect, as well as the advantages of bacteriophages over other forms of treatment, are presented. Conclusions. Therapy methods using bacteriophages in combination with antibacterial drugs can provide a higher therapeutic effect. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2360-3445 |
| Relation: | https://www.journalstudiesanthropology.ro/en/the-use-of-bacteriophages-in-the-treatment-of-staphylococcal-infection/; https://doaj.org/toc/2360-3445 |
| DOI: | 10.26758/14.1.21 |
| URL الوصول: | https://doaj.org/article/f818da60691146c3a096771310ee47ac |
| رقم الأكسشن: | edsdoj.f818da60691146c3a096771310ee47ac |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23603445 |
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| DOI: | 10.26758/14.1.21 |