دورية أكاديمية
P3.02 MORNING BLOOD PRESSURE SURGE, BLOOD PRESSURE VARIABILITY AND AORTIC STIFFNESS IN ESSENTIAL HYPERTENSION
العنوان: | P3.02 MORNING BLOOD PRESSURE SURGE, BLOOD PRESSURE VARIABILITY AND AORTIC STIFFNESS IN ESSENTIAL HYPERTENSION |
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المؤلفون: | G. Pucci, F. Battista, G. Bilo, G. Parati, G. Schillaci |
المصدر: | Artery Research, Vol 7, Iss 10 (2013) |
بيانات النشر: | BMC, 2013. |
سنة النشر: | 2013 |
المجموعة: | LCC:Specialties of internal medicine LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Morning blood pressure surge is associated with increased cardiovascular risk, possibly due to its ability to reflect short-term BP variability and/or its link with arterial stiffness. The link between morning BP surge and vascular stiffness is not defined. 689 untreated hypertensives (48±10 years, BP 149/92±17/10 mmHg) underwent c-f PWV and 24-h ambulatory BP measurement. Morning surge was calculated as: sleep-trough surge (STS, 2-hour average SBP after wake-up minus average of 3 SBP centered on the lowest nighttime reading), pre-awakening surge (PAS, 2-hour average SBP after wake-up minus 2-hour average SBP before wake-up), and rising BP surge (RBS, SBP on rising minus the lowest SBP in the 30’before). Average real variability (ARV, 24h average of the absolute differences between consecutive SBP), was considered a measure of short-term SBP variability. STS and RBS were directly correlated to cfPWV (r=0.17 and r=0.12,p39 mmHg) had higher age- and 24-h mean BP-adjusted cfPWV (9.73±2 vs 9.29±2 m/s, p=0.004), while no difference was found for the top quartile of PAS or RBS. In a multivariate regression, high STS values predicted a high cfPWV (β=0.08,p=0.038), independently of age, sex, 24-h mean BP and nocturnal BP reduction. After adding ARV (β=0.17,p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1876-4401 |
Relation: | https://www.atlantis-press.com/article/125938987/view; https://doaj.org/toc/1876-4401 |
DOI: | 10.1016/j.artres.2013.10.090 |
URL الوصول: | https://doaj.org/article/f8551cec1e934338a961669f2652fb34 |
رقم الأكسشن: | edsdoj.f8551cec1e934338a961669f2652fb34 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 18764401 |
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DOI: | 10.1016/j.artres.2013.10.090 |