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Effects of reusing baseline volumes of interest by applying (non-)rigid image registration on positron emission tomography response assessments.

التفاصيل البيبلوغرافية
العنوان: Effects of reusing baseline volumes of interest by applying (non-)rigid image registration on positron emission tomography response assessments.
المؤلفون: Floris H P van Velden, Ida A Nissen, Wendy Hayes, Linda M Velasquez, Otto S Hoekstra, Ronald Boellaard
المصدر: PLoS ONE, Vol 9, Iss 1, p e87167 (2014)
بيانات النشر: Public Library of Science (PLoS), 2014.
سنة النشر: 2014
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: OBJECTIVES: Reusing baseline volumes of interest (VOI) by applying non-rigid and to some extent (local) rigid image registration showed good test-retest variability similar to delineating VOI on both scans individually. The aim of the present study was to compare response assessments and classifications based on various types of image registration with those based on (semi)-automatic tumour delineation. METHODS: Baseline (n = 13), early (n = 12) and late (n = 9) response (after one and three cycles of treatment, respectively) whole body [(18)F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (PET/CT) scans were acquired in subjects with advanced gastrointestinal malignancies. Lesions were identified for early and late response scans. VOI were drawn independently on all scans using an adaptive 50% threshold method (A50). In addition, various types of (non-)rigid image registration were applied to PET and/or CT images, after which baseline VOI were projected onto response scans. Response was classified using PET Response Criteria in Solid Tumors for maximum standardized uptake value (SUV(max)), average SUV (SUV(mean)), peak SUV (SUV(peak)), metabolically active tumour volume (MATV), total lesion glycolysis (TLG) and the area under a cumulative SUV-volume histogram curve (AUC). RESULTS: Non-rigid PET-based registration and non-rigid CT-based registration followed by non-rigid PET-based registration (CTPET) did not show differences in response classifications compared to A50 for SUV(max) and SUV(peak), however, differences were observed for MATV, SUV(mean), TLG and AUC. For the latter, these registrations demonstrated a poorer performance for small lung lesions (
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC3904976?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0087167
URL الوصول: https://doaj.org/article/dcf8b224c1314882999a2d5b206cd6c7
رقم الأكسشن: edsdoj.f8b224c1314882999a2d5b206cd6c7
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0087167