دورية أكاديمية

Comparison of original and modified Q risk 2 risk score with Framingham risk score - An Indian perspective

التفاصيل البيبلوغرافية
العنوان: Comparison of original and modified Q risk 2 risk score with Framingham risk score - An Indian perspective
المؤلفون: Puneet Aggarwal, Santosh Kumar Sinha, Dibbendhu Khanra, Ranjit Kumar Nath, Jaskaran Gujral, Kranthi Kumar Reddy, Anindya Mukherjee
المصدر: Indian Heart Journal, Vol 73, Iss 3, Pp 353-358 (2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
المجموعة: LCC:Surgery
LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Q risk 2, Framingham risk score, Smokeless tobacco, Cardiovascular disease, Primary prevention, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Objective: No study among Indian population has proposed modification of existing cardiovascular disease (CVD) risk scores or novel risk scores as risk estimation using conventional risk calculators can’t be generalized because of epidemiological differences. Material and methods: A single center observational study was performed at a tertiary care center among participants having no evidence of CVD. Prevalence of various cardiac risk factors were analysed and 10-year risk was estimated using Framingham risk score (FRS), Q risk 2 score calculator (QRISK2) and Modified Q risk 2 (mQRISK2) which included smokeless tobacco consumption. QRISK2 and mQRISK2 were compared with FRS and participant’s eligibility for statin therapy as primary preventive measure was assessed. Results: Total of 4045 participants were enrolled from August 2016 to July 2019. 3520(87%) had no history of smoking in their lifetime while smokeless tobacco consumption was seen in 1153(28.5%), diabetes in 422(10.4%), hypertension in 1096(27.1%), obesity in 2035(50.3%), and family history of CVD in 353(8.7%) participants. High risk participants were found to be 826(20.4%), 627(15.5%), and 509(12.6%) by using FRS, mQRISK2 and QRISK2, whereas those eligible for statin therapy were maximum by mQRISK2 among 1323(32.7%) participants compared to QRISK2 (n = 1191; 29.4%) and FRS (n = 826; 20.4%) model. Krippendorff’s alpha for mQRISK2 was in better agreement with body mass index (BMI) and lipid FRS CVD scoring system as compared to QRISK2 risk model. Conclusion: CVD risk stratification based on smokeless tobacco use is first of its kind from this part of world and should be part of CV risk assessment.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0019-4832
Relation: http://www.sciencedirect.com/science/article/pii/S001948322100016X; https://doaj.org/toc/0019-4832
DOI: 10.1016/j.ihj.2021.01.016
URL الوصول: https://doaj.org/article/f8e59c7e51c14d2684ec2288a47f4587
رقم الأكسشن: edsdoj.f8e59c7e51c14d2684ec2288a47f4587
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00194832
DOI:10.1016/j.ihj.2021.01.016