دورية أكاديمية
High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases.
| العنوان: | High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases. |
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| المؤلفون: | Johannes Leitner, Sebastian Pelster, Veronika Schöpf, Anna S Berghoff, Ramona Woitek, Ulrika Asenbaum, Karl-Heinz Nenning, Georg Widhalm, Barbara Kiesel, Brigitte Gatterbauer, Karin Dieckmann, Peter Birner, Daniela Prayer, Matthias Preusser, Julia Furtner |
| المصدر: | PLoS ONE, Vol 13, Iss 11, p e0207849 (2018) |
| بيانات النشر: | Public Library of Science (PLoS), 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | ObjectivesThis study aimed to assess the correlation of temporal muscle thickness (TMT), measured on routine cranial magnetic resonance (MR) images, with lumbar skeletal muscles obtained on computed tomography (CT) images in brain metastasis patients to establish a new parameter estimating skeletal muscle mass on brain MR images.MethodsWe retrospectively analyzed the cross-sectional area (CSA) of skeletal muscles at the level of the third lumbar vertebra on computed tomography scans and correlated these values with TMT on MR images of the brain in two independent cohorts of 93 lung cancer and 61 melanoma patients (overall: 154 patients) with brain metastases.ResultsPearson correlation revealed a strong association between mean TMT and CSA in lung cancer and melanoma patients with brain metastases (0.733; pConclusionOur data indicate that TMT, measured on routine cranial MR images, is a useful surrogate parameter for the estimation of skeletal muscle mass in patients with brain metastases. Thus, TMT may be useful for prognostic assessment, treatment considerations, and stratification or a selection factor for clinical trials in patients with brain metastases. Further studies are needed to assess the association between TMT and clinical frailty parameters, and the usefulness of TMT in patients with primary brain tumors. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0207849 |
| URL الوصول: | https://doaj.org/article/f949238bd5ee4fc38522dfdf1cebe722 |
| رقم الأكسشن: | edsdoj.f949238bd5ee4fc38522dfdf1cebe722 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0207849 |