دورية أكاديمية
Worldwide Increasing Incidence of Thyroid Cancer: Update on Epidemiology and Risk Factors
العنوان: | Worldwide Increasing Incidence of Thyroid Cancer: Update on Epidemiology and Risk Factors |
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المؤلفون: | Gabriella Pellegriti, Francesco Frasca, Concetto Regalbuto, Sebastiano Squatrito, Riccardo Vigneri |
المصدر: | Journal of Cancer Epidemiology, Vol 2013 (2013) |
بيانات النشر: | Wiley, 2013. |
سنة النشر: | 2013 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | Medicine |
الوصف: | Background. In the last decades, thyroid cancer incidence has continuously and sharply increased all over the world. This review analyzes the possible reasons of this increase. Summary. Many experts believe that the increased incidence of thyroid cancer is apparent, because of the increased detection of small cancers in the preclinical stage. However, a true increase is also possible, as suggested by the observation that large tumors have also increased and gender differences and birth cohort effects are present. Moreover, thyroid cancer mortality, in spite of earlier diagnosis and better treatment, has not decreased but is rather increasing. Therefore, some environmental carcinogens in the industrialized lifestyle may have specifically affected the thyroid. Among potential carcinogens, the increased exposure to medical radiations is the most likely risk factor. Other factors specific for the thyroid like increased iodine intake and increased prevalence of chronic autoimmune thyroiditis cannot be excluded, while other factors like the increasing prevalence of obesity are not specific for the thyroid. Conclusions. The increased incidence of thyroid cancer is most likely due to a combination of an apparent increase due to more sensitive diagnostic procedures and of a true increase, a possible consequence of increased population exposure to radiation and to other still unrecognized carcinogens. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1687-8558 1687-8566 |
Relation: | https://doaj.org/toc/1687-8558; https://doaj.org/toc/1687-8566 |
DOI: | 10.1155/2013/965212 |
URL الوصول: | https://doaj.org/article/def99827baa04ca1880c30e45c738807 |
رقم الأكسشن: | edsdoj.f99827baa04ca1880c30e45c738807 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16878558 16878566 |
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DOI: | 10.1155/2013/965212 |