دورية أكاديمية
Lorazepam as a Cause of Drug-Induced Liver Injury
| العنوان: | Lorazepam as a Cause of Drug-Induced Liver Injury |
|---|---|
| المؤلفون: | Toshio Arai, Kazutoyo Kogi, Yuki Honda, Takao Suzuki, Koji Kawai, Masako Okamoto, Takahiro Fujioka, Nobuhiro Murata |
| المصدر: | Case Reports in Gastroenterology, Vol 12, Iss 2, Pp 546-550 (2018) |
| بيانات النشر: | Karger Publishers, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Lorazepam, Depression, Drug-induced liver injury, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Lorazepam is a benzodiazepine derivative that is globally used for the therapy of anxiety and insomnia. A 51-year-old Japanese man with yellowish discoloration of the eyes and skin and pruritus was admitted due to liver dysfunction. He had taken lorazepam approximately 5 months prior to this admission. The clinical presentation and pathologic findings in the liver were consistent with drug-induced liver injury. After cessation of lorazepam, treatment with Stronger neo-minophagen C and ursodeoxycholic acid was started, and his liver injury resolved after 59 days. This case must serve as a warning to physicians to be aware of the possibility of unexpected liver injury caused by lorazepam. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1662-0631 00049220 |
| Relation: | https://www.karger.com/Article/FullText/492209; https://doaj.org/toc/1662-0631 |
| DOI: | 10.1159/000492209 |
| URL الوصول: | https://doaj.org/article/ef9b486eed7a45e0bc911ebd582cb72c |
| رقم الأكسشن: | edsdoj.f9b486eed7a45e0bc911ebd582cb72c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16620631 00049220 |
|---|---|
| DOI: | 10.1159/000492209 |