دورية أكاديمية
Exploring self-reported visual function and vision-related anxiety in patients with RPGR-associated retinal degeneration
| العنوان: | Exploring self-reported visual function and vision-related anxiety in patients with RPGR-associated retinal degeneration |
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| المؤلفون: | Nuno Gouveia, Oluji Chukwunalu, Carolina Oliveira, C. Henrique Alves, Rufino Silva, Joaquim Murta, João Pedro Marques |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Patient-reported outcomes, Retinitis pigmentosa, RPGR, Anxiety, Medicine, Science |
| الوصف: | Abstract Variants in the retinitis pigmentosa GTPase regulator (RPGR) gene are responsible for the majority of X-linked retinitis pigmentosa cases, which not only affects male patients but also some heterozygous females. Vision-related disability and anxiety of patients with RPGR-associated retinal degeneration have never been explored before. This study aimed to evaluate self-reported visual function and vision-related anxiety in a Portuguese cohort of male and female patients with RPGR-associated retinal degeneration using two validated patient-reported outcome measures. Cross-sectional data of thirty-two genetically-tested patients was examined, including scores of the Michigan retinal degeneration questionnaire (MRDQ) and Michigan vision-related anxiety questionnaire. Patients were classified according to retinal phenotypes in males (M), females with male phenotype (FM), and females with radial or focal pattern. Both M and FM revealed higher rod-function and cone-function anxiety scores (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-66170-2 |
| URL الوصول: | https://doaj.org/article/dfaeb4784cab4498b3215af36880512d |
| رقم الأكسشن: | edsdoj.faeb4784cab4498b3215af36880512d |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-024-66170-2 |