دورية أكاديمية

Prenatal hepatitis C screening, diagnoses, and follow-up testing in British Columbia, 2008-2019.

التفاصيل البيبلوغرافية
العنوان: Prenatal hepatitis C screening, diagnoses, and follow-up testing in British Columbia, 2008-2019.
المؤلفون: Margo E Pearce, Amanda Yu, Maria Alvarez, Sofia R Bartlett, Mawuena Binka, Dahn Jeong, Emilia Clementi, Prince Adu, James Wilton, Eric M Yoshida, Neora Pick, Jane A Buxton, Jason Wong, Agatha Jassem, Mel Krajden, Naveed Z Janjua
المصدر: PLoS ONE, Vol 15, Iss 12, p e0244575 (2020)
بيانات النشر: Public Library of Science (PLoS), 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: ObjectiveCurrent guidelines in British Columbia recommend prenatal screening for hepatitis C antibodies (anti-HCV) if risk factors are present. We aimed to estimate frequency of prenatal anti-HCV testing, new diagnoses, repeated and follow-up testing among BC women.MethodsBC Centre for Disease Control Public Health Laboratory data estimated the number of BC women (assigned female at birth or unknown sex) aged 13-49 who received routine prenatal serological screening (HIV, hepatitis B, syphilis and rubella) from 2008-2019. Anti-HCV tests ordered the same day as routine prenatal screens were considered prenatal anti-HCV tests. Assessment of follow-up was based on HCV RNA and/or genotype testing within one year of new prenatal anti-HCV diagnoses.ResultsIn 2019, 55,202 routine prenatal screens were carried out for 50,392 BC women. Prenatal anti-HCV tests increased significantly, from 19.6% (9,704/49,515) in 2008 to 54.6% (27,516/50,392) in 2019 (pConclusionPrenatal anti-HCV testing increased substantially over the study period. However, new HCV diagnoses remained relatively stable, suggesting that a considerable proportion of BC women with low or no risk are being screened as part of prenatal care. The vast majority of women with new HCV diagnoses receive appropriate follow-up HCV RNA and genotype testing, which may indicate interest in HCV treatment. These findings contribute to the discussion around potential for prenatal anti-HCV screening in an effort to eliminate HCV.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0244575
URL الوصول: https://doaj.org/article/efb0dcbd81414168b481789648878594
رقم الأكسشن: edsdoj.fb0dcbd81414168b481789648878594
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0244575