دورية أكاديمية
Prenatal hepatitis C screening, diagnoses, and follow-up testing in British Columbia, 2008-2019.
العنوان: | Prenatal hepatitis C screening, diagnoses, and follow-up testing in British Columbia, 2008-2019. |
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المؤلفون: | Margo E Pearce, Amanda Yu, Maria Alvarez, Sofia R Bartlett, Mawuena Binka, Dahn Jeong, Emilia Clementi, Prince Adu, James Wilton, Eric M Yoshida, Neora Pick, Jane A Buxton, Jason Wong, Agatha Jassem, Mel Krajden, Naveed Z Janjua |
المصدر: | PLoS ONE, Vol 15, Iss 12, p e0244575 (2020) |
بيانات النشر: | Public Library of Science (PLoS), 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | ObjectiveCurrent guidelines in British Columbia recommend prenatal screening for hepatitis C antibodies (anti-HCV) if risk factors are present. We aimed to estimate frequency of prenatal anti-HCV testing, new diagnoses, repeated and follow-up testing among BC women.MethodsBC Centre for Disease Control Public Health Laboratory data estimated the number of BC women (assigned female at birth or unknown sex) aged 13-49 who received routine prenatal serological screening (HIV, hepatitis B, syphilis and rubella) from 2008-2019. Anti-HCV tests ordered the same day as routine prenatal screens were considered prenatal anti-HCV tests. Assessment of follow-up was based on HCV RNA and/or genotype testing within one year of new prenatal anti-HCV diagnoses.ResultsIn 2019, 55,202 routine prenatal screens were carried out for 50,392 BC women. Prenatal anti-HCV tests increased significantly, from 19.6% (9,704/49,515) in 2008 to 54.6% (27,516/50,392) in 2019 (pConclusionPrenatal anti-HCV testing increased substantially over the study period. However, new HCV diagnoses remained relatively stable, suggesting that a considerable proportion of BC women with low or no risk are being screened as part of prenatal care. The vast majority of women with new HCV diagnoses receive appropriate follow-up HCV RNA and genotype testing, which may indicate interest in HCV treatment. These findings contribute to the discussion around potential for prenatal anti-HCV screening in an effort to eliminate HCV. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 |
Relation: | https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0244575 |
URL الوصول: | https://doaj.org/article/efb0dcbd81414168b481789648878594 |
رقم الأكسشن: | edsdoj.fb0dcbd81414168b481789648878594 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 |
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DOI: | 10.1371/journal.pone.0244575 |