دورية أكاديمية
Genetic Profiling of the Plasmodium falciparum Population Using Antigenic Molecular Markers
| العنوان: | Genetic Profiling of the Plasmodium falciparum Population Using Antigenic Molecular Markers |
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| المؤلفون: | Purva Gupta, Ruchi Singh, Haris Khan, Adil Raza, Veena Yadavendu, R. M. Bhatt, Vineeta Singh |
| المصدر: | The Scientific World Journal, Vol 2014 (2014) |
| بيانات النشر: | Hindawi Limited, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Technology LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Technology, Medicine, Science |
| الوصف: | About 50% of malaria infections in India are attributed to Plasmodium falciparum but relatively little is known about the genetic structure of the parasite populations. The molecular genotyping of the parasite populations by merozoite surface protein (msp1 and msp2) and glutamate-rich protein (glurp) genes identifies the existing parasite population in the regions which help in understanding the molecular mechanisms involved in the parasite’s drive for survival. This study reveals the genetic profile of the parasite population in selected regions across the country with varying degree of endemicity among them. We also report the prevalence of Pfcrt mutations in this parasite population to evaluate the pattern of drug resistance development in them. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2356-6140 1537-744X |
| Relation: | https://doaj.org/toc/2356-6140; https://doaj.org/toc/1537-744X |
| DOI: | 10.1155/2014/140867 |
| URL الوصول: | https://doaj.org/article/fb7c5fd8280f4f3f8be0edca2a8d7394 |
| رقم الأكسشن: | edsdoj.fb7c5fd8280f4f3f8be0edca2a8d7394 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23566140 1537744X |
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| DOI: | 10.1155/2014/140867 |