دورية أكاديمية
Refractory/Resistant Cytomegalovirus Infection in Transplant Recipients: An Update
العنوان: | Refractory/Resistant Cytomegalovirus Infection in Transplant Recipients: An Update |
---|---|
المؤلفون: | Léna Royston, Genovefa A. Papanicolaou, Dionysios Neofytos |
المصدر: | Viruses, Vol 16, Iss 7, p 1085 (2024) |
بيانات النشر: | MDPI AG, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Microbiology |
مصطلحات موضوعية: | cytomegalovirus (CMV), transplant recipients, refractory infection, resistant infection, letermovir, maribavir, Microbiology, QR1-502 |
الوصف: | Despite the significant progress made, CMV infection is one of the most frequent infectious complications in transplant recipients. CMV infections that become refractory or resistant (R/R) to the available antiviral drugs constitute a clinical challenge and are associated with increased morbidity and mortality. Novel anti-CMV therapies have been recently developed and introduced in clinical practice, which may improve the treatment of these infections. In this review, we summarize the treatment options for R/R CMV infections in adult hematopoietic cell transplant and solid organ transplant recipients, with a special focus on newly available antiviral agents with anti-CMV activity, including maribavir and letermovir. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 16071085 1999-4915 |
Relation: | https://www.mdpi.com/1999-4915/16/7/1085; https://doaj.org/toc/1999-4915 |
DOI: | 10.3390/v16071085 |
URL الوصول: | https://doaj.org/article/fc5c15de2fcd41c1b0d23d4a0286aac7 |
رقم الأكسشن: | edsdoj.fc5c15de2fcd41c1b0d23d4a0286aac7 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16071085 19994915 |
---|---|
DOI: | 10.3390/v16071085 |