دورية أكاديمية
Intravenous immunoglobulin for patients with unexplained recurrent implantation failure: a 6-year single center retrospective review of clinical outcomes
| العنوان: | Intravenous immunoglobulin for patients with unexplained recurrent implantation failure: a 6-year single center retrospective review of clinical outcomes |
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| المؤلفون: | Einav Kadour Peero, Shorooq Banjar, Rabea Khoudja, Shaonie Ton-leclerc, Coralie Beauchamp, Joanne Benoit, Marc Beltempo, Michael H. Dahan, Phil Gold, Isaac Jacques Kadoch, Wael Jamal, Carl Laskin, Neal Mahutte, Simon Phillips, Camille Sylvestre, Shauna Reinblatt, Bruce D. Mazer, William Buckett, Genevieve Genest |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Unexplained recurrent implantation failure, Intravenous immunoglobulin, Reproductive immunology, Immune-mediated recurrent implantation failure, Medicine, Science |
| الوصف: | Abstract The effectiveness of intravenous immunoglobulin (IVIg) for patients with unexplained recurrent implantation failure (uRIF) remains debated. We retrospectively analysed outcomes of uRIF patients treated with IVIg compared to a separate control uRIF cohort within our center (01/2014–12/2021). Primary outcomes included live birth, miscarriage, or transfer failure. We documented IVIg side effects and maternal/fetal outcomes. Logistic regression analysis was used to assess for association of IVIg exposure with outcomes and adjust for confounders. The study included 143 patients, with a 2:1 ratio of controls to patients receiving IVIg treatment. Patient characteristics were similar between groups. There was higher live birth rate (LBR) in patients receiving IVIg (32/49; 65.3%) compared to controls (32/94; 34%); p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-54423-z |
| URL الوصول: | https://doaj.org/article/eafcc417c6e24b9d93307875f06a604f |
| رقم الأكسشن: | edsdoj.fcc417c6e24b9d93307875f06a604f |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-024-54423-z |