دورية أكاديمية
Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
العنوان: | Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis |
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المؤلفون: | Dongryul Kim, Da Won Kim, Yeon Hee Lee, So Yeon Park, Young Woo Song, Hyeonoh Shin, Hye Eun Yoon, Hoon Suk Park, Bum Soon Choi, Byung Soo Kim, Tae Hyun Ban, Seok Joon Shin |
المصدر: | Journal of International Medical Research, Vol 49 (2021) |
بيانات النشر: | SAGE Publishing, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine (General) |
مصطلحات موضوعية: | Medicine (General), R5-920 |
الوصف: | Objective High monocyte to high-density lipoprotein cholesterol ratio (MHR) is known to be a risk factor for cardiovascular (CV) complications. We aimed to evaluate the relationship between MHR and CV outcomes in patients commencing dialysis. Methods The medical records of patients who started maintenance dialysis between January 2006 and July 2017 were reviewed. The primary outcomes were all-cause mortality and overall CV mortality and the secondary outcomes were CV event-free survival and the incidence of CV complications. Results Five hundred ninety-seven patients were enrolled and allocated to low- or high-MHR groups. All-cause mortality did not differ between the groups during a mean follow-up period of 3.9 years. In addition, overall CV mortality did not differ between the groups. However, CV event-free survival was significantly lower in the high-MHR group than in the low-MHR group (47.5% vs . 59.0%). Multivariate Cox regression analysis showed that high MHR was an independent predictor of CV events (HR 1.886, 95% CI 1.015–3.505). Conclusion High MHR at the time of initiation of dialysis may represent a useful predictor of CV complications. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1473-2300 03000605 |
Relation: | https://doaj.org/toc/1473-2300 |
DOI: | 10.1177/03000605211058861 |
URL الوصول: | https://doaj.org/article/fce8a33b0644476fb8b2213f97c0fca1 |
رقم الأكسشن: | edsdoj.fce8a33b0644476fb8b2213f97c0fca1 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14732300 03000605 |
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DOI: | 10.1177/03000605211058861 |