دورية أكاديمية
Stimulation of Biological Structures on the Nanoscale Using Interfaces with Large Built-In Spontaneous Polarizations
| العنوان: | Stimulation of Biological Structures on the Nanoscale Using Interfaces with Large Built-In Spontaneous Polarizations |
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| المؤلفون: | Nida Zia, Michael Stroscio, Mitra Dutta |
| المصدر: | Materials, Vol 17, Iss 10, p 2332 (2024) |
| بيانات النشر: | MDPI AG, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Technology LCC:Electrical engineering. Electronics. Nuclear engineering LCC:Engineering (General). Civil engineering (General) LCC:Microscopy LCC:Descriptive and experimental mechanics |
| مصطلحات موضوعية: | Debye screening, spontaneous polarization, ion channels, Technology, Electrical engineering. Electronics. Nuclear engineering, TK1-9971, Engineering (General). Civil engineering (General), TA1-2040, Microscopy, QH201-278.5, Descriptive and experimental mechanics, QC120-168.85 |
| الوصف: | The electric potential stimulation of biological structures in aqueous environments is well-known to be a result of the gating of voltage-gated ion channels. Such voltage-gated ion channels are ubiquitous in the membranes of a wide variety of cells and they play central roles in a wide variety of sensing mechanisms and neuronal functions in biological systems. Experimental studies of ion-channel gating are frequently conducted using path-clamp techniques by placing a cumbersome external electrode in the vicinity of the extracellular side of the ion channel. Recently, it has been demonstrated that laser-induced polarization of nanoscale quantum dots can produce voltage sufficient to gate voltage-gated ion channels. This study specifically focuses on a new method of gating voltage-gated ion channels using 2D structures made of materials exhibiting large naturally occurring spontaneous polarizations, thereby eliminating the need for an external electrode or an illuminating laser. The work presents the use of self-polarizing semiconductor flakes, namely, 2H-SiC, ZnO, and GaN, to produce electric potential that is sufficient to gate voltage-gated ion channels when existing in proximity to it. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 17102332 1996-1944 |
| Relation: | https://www.mdpi.com/1996-1944/17/10/2332; https://doaj.org/toc/1996-1944 |
| DOI: | 10.3390/ma17102332 |
| URL الوصول: | https://doaj.org/article/adfddaa8c9184201a0c8b2fccff0a07a |
| رقم الأكسشن: | edsdoj.fddaa8c9184201a0c8b2fccff0a07a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17102332 19961944 |
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| DOI: | 10.3390/ma17102332 |