دورية أكاديمية
Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme
| العنوان: | Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme |
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| المؤلفون: | Lynn N Jena, Lindsey A Bennie, Emma M McErlean, Sreekanth Pentlavalli, Kim Glass, James F Burrows, Vicky L Kett, Niamh E Buckley, Jonathan A Coulter, Nicholas J Dunne, Helen O McCarthy |
| المصدر: | Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-18 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biotechnology LCC:Medical technology |
| مصطلحات موضوعية: | Glioblastoma Multiforme, Bisphosphonate, Nanoparticles, Anticancer, RALA peptide, Nanomedicine, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5 |
| الوصف: | Abstract Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct anticancer effects in a number of tumour types including GBM. In this study, a nano-formulation with the RALA peptide was used to complex the N-BP, alendronate (ALN) into nanoparticles (NPs) |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1477-3155 |
| Relation: | https://doaj.org/toc/1477-3155 |
| DOI: | 10.1186/s12951-021-00856-x |
| URL الوصول: | https://doaj.org/article/ff00e18b61e540388dddf96e6bc47180 |
| رقم الأكسشن: | edsdoj.ff00e18b61e540388dddf96e6bc47180 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14773155 |
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| DOI: | 10.1186/s12951-021-00856-x |