Objective: To examine the resilience of parents of children with congenital heart disease and to investigate socio-demographic factors that may influence parents’ resilience. Methods: This is a web-based survey study using a cross-sectional design. A purposive sampling method was utilized to recruit 515 parents who care for children with congenital heart disease. Resilience was assessed using the Dispositional Resilience Scale-Ⅱ. Based on expert-interviews, a questionnaire was designed to collect socio-demographic data. Descriptive statistics, factor analysis, and linear regressions were used to analyze data. Results: A total of 413 parents completed the survey study. The mean resilience score was 3.75 (SD = 0.61; range = 1.89–4.89) with higher scores indicating higher resilience. The linear regression models demonstrated that parents who had lower education levels and lower gross household income had lower resilience (P