The discovery of (1R, 3R)-1-(3-chloro-5-fluorophenyl)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile, a potent and selective agonist of human transient receptor potential cation channel subfamily m member 5 (TRPM5) and evaluation of as a potential gastrointestinal prokinetic agent

التفاصيل البيبلوغرافية
العنوان:	The discovery of (1R, 3R)-1-(3-chloro-5-fluorophenyl)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile, a potent and selective agonist of human transient receptor potential cation channel subfamily m member 5 (TRPM5) and evaluation of as a potential gastrointestinal prokinetic agent
المؤلفون:	Sabat, M., Raveglia, L.F., Aldegheri, L., Barilli, A., Bianchi, F., Brault, L., Brodbeck, D., Feriani, A., Lingard, I., Miura, J., Myers, R., Piccoli, L., Tassini, S., Tyhonas, J., Ton-Nu, T., Wang, H., Virginio, C.
المصدر:	In Bioorganic & Medicinal Chemistry 15 December 2022 76
قاعدة البيانات:	ScienceDirect

الوصف
تدمد:	09680896
DOI:	10.1016/j.bmc.2022.117084