كتاب
DNA damage: from causes to cures
| العنوان: | DNA damage: from causes to cures |
|---|---|
| المؤلفون: | Biochemical Society (Great Britain). Symposium (76th : 2008 : Robinson College, University of Cambridge) |
| المساهمون: | Bowater, Richard P., Borts, Rhona H., White, Malcolm F., Biochemical Society (Great Britain) |
| بيانات النشر: | London : Portland Press, c2009. |
| سنة النشر: | 2009 |
| وصف مادي: | xiv, 162 p. : ill. (some col.) ; 26 cm. |
| سلاسل: | Biochemical Society Symposia |
| مصطلحات موضوعية: | DNA Repair -- physiology., DNA Damage -- physiology., DNA Damage., DNA Repair., DNA repair -- Congresses., DNA damage -- Congresses., Congresses., Conference papers and proceedings. |
| الوصف: | "In order to maintain genome integrity, it is essential that any DNA damage is repaired. This is achieved in diverse ways in all cells to ensure their survival. There is a large repertoire of proteins that remove and repair DNA damage. However, sometimes these processes do not function correctly, leading to genome instability, which is known to cause a number of hereditary diseases in humans. DNA Damage: from Causes to Cures features contributions from the invited speakers at the Biochemical Society's Annual Symposium held at Robinson College, Cambridge, on 15-18 December 2008. The featured chapters, written by experts in the field, showcase studies of DNA repair and genome instability, with a particular focus on how research is developing a deeper understanding of the causes and potential cures of DNA damage"--Publisher's description. |
| ملاحظة حول المحتويات: | The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk : genotype-phenotype correlations / Janet Hall [and others] -- Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited infammatory disease / Tomas Lindahl [and others] -- Repairing DNA double-strand breaks by the prokaryotic non-homologous end-joining pathway / Nigel C. Brissett and Aidan J. Doherty -- Structure, function and evolution of the XPD family of iron-sulfur-containing 5'-3' DNA helicases / Malcolm F. White -- Genomic instability and cancer : lessons from analysis of Bloom's syndrome / Miranda Payne and Ian D. Hickson -- Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation / Uttiya Basu [and others] -- The impact of heterochromatin on DSB repair / Aaron A. Goodarzi, Angela T. Noon, and Penny A. Jeggo -- Short-patch single-strand break repair in ataxia oculomotor apraxia-1 / John J. Reynolds, Sherif F. El-Khamisy, and Keith W. Caldecott -- A molecular model for drug binding to tandem repeats of telomeric G-quadruplexes / Shozeb M. Haider and Stephen Neidle -- The role of recombination in telomere length maintenance / Nicola J. Royle [and others] -- Understanding the functions of BRCA1 in the DNA-damage response / Maximina H. Yun and Kevin Hiom -- PCNA on the crossroad of cancer / Ivaylo Stoimenov and Thomas Helleday. |
| Original Identifier: | ocn465362591 |
| نوع الوثيقة: | Book |
| اللغة: | English |
| ردمك: | 978-1-85578-173-3 1-85578-173-5 |
| حقوق: | This record is part of the Harvard Library Bibliographic Dataset, which is provided by the Harvard Library under its Bibliographic Dataset Use Terms and includes data made available by, among others, OCLC Online Computer Library Center, Inc. and the Library of Congress. |
| ملاحظات: | "BSSYAT 76"--Cover. Based on papers presented at the 2008 Biochemical Society Annual Symposium entitled "DNA damage: from causes to cures", held at Robinson College, University of Cambridge, on 15-17 December 2008. Includes bibliographical references and index. |
| رقم الأكسشن: | edshlc.012139857.9 |
| قاعدة البيانات: | Harvard Library Bibliographic Dataset |
| ردمك: | 9781855781733 1855781735 |
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