Cardiac mechano-electric coupling and arrhythmias

التفاصيل البيبلوغرافية
العنوان: Cardiac mechano-electric coupling and arrhythmias
المؤلفون: Kohl, Peter, MD.
المساهمون: Sachs, Frederick., Franz, M. R. (Michael R.), 1949-, Kohl, Peter, MD. Cardiac mechano-electric feedback and arrhythmias.
بيانات النشر: Oxford ; New York : Oxford University Press, 2011. 2nd ed.
سنة النشر: 2011
وصف مادي: xxx, 477 p. : ill. (some col.) ; 24 cm.
مصطلحات موضوعية: Heart -- Contraction., Arrhythmia., Heart conduction system., Biological control systems., Myocardium., Heart Conduction System -- physiopathology., Heart Conduction System -- physiology., Arrhythmias, Cardiac.
ملاحظة حول المحتويات: Basic science, section I: sub-cellular mechanisms of cardiac mechano-electric coupling -- Evolutionary origins of stretch-activated ion channels -- Stretch-activated channels in the heart -- The mechano-gated K2P channel TREK-1 in the cardiovascular system -- Cell volume-sensitive ion channels and transporters in cardiac myocytes -- The response of cardiac muscle to stretch: calcium and force -- Stretch effects on second messengers -- Functional implications of myocyte architecture -- Mechanical modulation of pacemaker electrophysiology -- Mechano-electric coupling in working cardiomyocytes: diastolic and systolic effects -- Mechano-sensitivity of pulmonary vein cells: implications for atrial arrhythmogenesis -- Heterogeneity of sarcomere length and function as a cause of arrhythmogenic calcium waves -- Cellular mechanisms of arrhythmogenic cardiac alternans --
Remodeling of gap junctions in ventricular myocardium: effects of cell-to-cell adhesion, mediators of hypertrophy and mechanical forces -- The origin of fibroblasts, ECM and potential contributions to cardiac mechano-electric coupling -- Advantages and pitfalls of cell cultures as model systems to study cardiac mechanoelectric coupling -- Activation sequence of cardiac muscle in simplified experimental models: relevance for cardiac mechano electric coupling -- Acute stretch effects on atrial electro-physiology -- Stretch effects on potassium accumulation and alternans in pathological myocardium -- The effects of wall stretch on ventricular conduction and refractoriness in the whole heart -- Mechanical triggers of long-term ventricular electrical remodeling -- Mechanisms of mechanical pre- and postconditioning -- Mechano-electric coupling in chronic atrial fibrillation -- Mechanically induced pulmonary vein ectopy -- insight from animal models --
Regional variation in mechano-electric coupling: the right ventricle -- Mechanical induction of arrhythmia in the ex-situ heart: insight into commotio cordis -- Arrhythmias in murine models of the mechanically impaired heart -- Studying cardiac mechano-sensitivity in man -- Mathematical models of cardiac structure and function: mechanistic insights from models of heart failure -- Mathematical models of human atrial mechano-electrical coupling and arrhythmias -- Mathematical models of ventricular mechano-electric coupling and arrhythmia -- Load dependence of ventricular repolarisation -- Is the U wave in the electrocardiogram a mechanoelectrical phenomenon? -- Mechanical modulation of cardiac function: role of the pericardium -- Mechanically-induced electrical remodelling in human atrium -- Drug effects and atrial fibrillation: potential and limitations -- Stretch as a mechanism linking short- and long-term electrical remodeling in the ventricles.
Volume and pressure overload and ventricular arrhythmogenesis -- Stretch effects on fibrillation dynamics -- Commotio cordis: sudden death from blows to the chest wall -- Repolarization changes in the synchronously and dys-synchronously contracting failing heart -- Ventricular arrhythmias in heart failure: link to hemodynamic load -- Mechanical heterogeneity and aftercontractions as trigger of torsades des pointes -- Stretch-induced arrhythmias in ischaemia -- Antiarrhythmic effects of acute mechanical stimulation -- Termination of arrhythmias by haemodynamic unloading -- Mechanical modulation of defibrillation and resuscitation efficacy -- Anti- and pro-arrhythmic effects of cardiac assist device implantation -- Anti- and pro-arrhythmic effects of cardiac resynchronization therapy -- Evidence for mechano-electric coupling from clinical trials on AF -- Evidence for mechano-electric coupling from clinical trials in heart failure -- Mechano-electrical coupling and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy -- Evidence for mechano-electric coupling from clinical trials on cardiac resynchronization therapy -- Mechano-electric coupling in patients treated with ventricular assist devices: insights from individual cases and clinical trials -- Measuring strain of structural proteins in vivo in real time -- Roles of SAC beyond M-E transaction -- Distributions of myocyte stress, strain and work in normal and infarcted ventricles -- Evolving concepts in measuring ventricular strain in the canine and human hearts: non-invasive imaging -- Evolving concepts in measuring ventricular strain in the human heart: impedance measurements -- Mechanosensitive channel blockers: a new class of antiarrhythmic drugs?
Original Identifier: ocn693810852
نوع الوثيقة: Book
اللغة: English
ردمك: 978-0-19-957016-4
0-19-957016-7
حقوق: This record is part of the Harvard Library Bibliographic Dataset, which is provided by the Harvard Library under its Bibliographic Dataset Use Terms and includes data made available by, among others, OCLC Online Computer Library Center, Inc. and the Library of Congress.
ملاحظات: Rev. ed. of: Cardiac mechano-electric feedback and arrhythmias. 2005.

Includes bibliographical references and index.
رقم الأكسشن: edshlc.013099723.4
قاعدة البيانات: Harvard Library Bibliographic Dataset
الوصف
ردمك:9780199570164
0199570167