مورد إلكتروني
The endocannabinoid system in migraine: from bench to pharmacy and back.
| العنوان: | The endocannabinoid system in migraine: from bench to pharmacy and back. |
|---|---|
| المصدر: | Department of Neurology Faculty Papers |
| بيانات النشر: | Jefferson Digital Commons 2019-06-01T07:00:00Z |
| تفاصيل مُضافة: | Tassorelli, Cristina Greco, Rosaria Silberstein, Stephen D. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | PURPOSE OF REVIEW: Migraine is a common, highly disabling disorder. Its treatment involves acute and preventive therapy. Many of available preventive medications are not well tolerated, which results in poor compliance and limited effectiveness. Cannabinoids have been proposed for the treatment of migraine but their efficacy and tolerability are controversial. RECENT FINDINGS: Cannabinoids modulate functions and activity of signaling pathways that have a key role in pain control. Growing preclinical evidence and initial clinical findings suggest that modulation of the endocannabinoid system, via endogenous or exogenous cannabinoids may be relevant for migraine via multiple mechanisms. SUMMARY: The endocannabinoid system qualifies as an interesting area of research worth exploration in the quest for therapeutic targets for the treatment of migraine. |
| مصطلحات الفهرس: | endogenous and exogenous cannabinoids, trigeminovascular system, pain, Medicine and Health Sciences, Neurology, article |
| URL: | |
| الإتاحة: | Open access content. Open access content |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | TVJ oai:jdc.jefferson.edu:neurologyfp-1194 1105813358 |
| المصدر المساهم: | THOMAS JEFFERSON UNIV From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1105813358 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |