Studies examining the anti-aging effects of fullerenes
| العنوان: | Studies examining the anti-aging effects of fullerenes |
|---|---|
| المؤلفون: | Turner, Ashley R. |
| تفاصيل مُضافة: | NC Digital Online Collection of Knowledge and Scholarship (NCDOCKS) |
| وصف مادي: | 1 online resource (vii, 91 pages) : illustrations |
| مستخلص: | "Research on aging has been invigorated by recent findings suggesting certain mutations in various invertebrate models (yeast, worms, and flies) can slow down aging and improve healthspan. Reactive Oxygen Species (ROS) production and manipulation of the nutrient-sensing [mammalian (originally) or mechanistic target of rapamycin] mTOR signaling pathway have all been linked to aging and age-related diseases. Thus, identifying ways to interfere in these pathways may represent a promising avenue to increase longevity and improve healthspan in mammals. Fullerenes are a class of nanomaterials best known for their ability to significantly extend mammalian lifespan and cognitive function as shown in both mice and rats. Thus, the goal of this proposal is to determine possible mechanisms of how fullerenes extend lifespan focusing on mTOR signaling pathways and anti-oxidant capabilities to slow down aging and improve healthspan."--Abstract from author supplied metadata |
| الموضوعات: | Aging Prevention., Fullerenes Therapeutic use., Antioxidants Therapeutic use., Vieillissement Prévention., Fullerènes Emploi en thérapeutique., Antioxydants Emploi en thérapeutique., Aging Prevention., Antioxidants Therapeutic use., Fullerenes Therapeutic use. |
| مصطلحات الفهرس: | Academic theses., Academic theses., Thèses et écrits académiques. |
| URL: | |
| ملاحظة: | Directed by Christopher Kepley; submitted to the Joint School of Nanoscience and Nanoengineering. Available online via NCDOCKS. Title from PDF title page (viewed July 8, 2019). Includes bibliographical references (pages 73-83). |
| أرقام أخرى: | NGU oai:libres.uncg.edu/21982 1107492688 |
| المصدر المساهم: | From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1107492688 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |