مورد إلكتروني
Cytomegalovirus reactivation in a critically ill patient: a case report
| العنوان: | Cytomegalovirus reactivation in a critically ill patient: a case report |
|---|---|
| المصدر: | Journal of Medical Case Reports |
| بيانات النشر: | BioMed Central International 2018 |
| تفاصيل مُضافة: | Demirkol, Demet; Kavgacı, Umay; Babaoğlu, Burcu; Tanju, Serhan; Sözmen, Banu Oflaz; Tekin, Süda School of Medicine Department of Pediatrics; Department of Thoracic Surgery; Department of Clinical Microbiology and Infectious Diseases |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Background: The aim of this case report is to discuss diagnostic workup and clinical management of cytomegalovirus reactivation in a critically ill immunocompetent pediatric patient. Case presentation: A 2-year-old white boy who had no medical history presented with respiratory distress and fever. His Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction scores were 20 and 11, respectively. Our preliminary diagnosis was multiple organ dysfunction secondary to sepsis. Antibiotic treatment was started; he was intubated and artificially ventilated. Norepinephrine infusion was started. Hemophagocytic lymphohistiocytosis was diagnosed because our patient had elevated levels of serum ferritin, bicytopenia, splenomegaly, fever (> 38.5 °C), and hemophagocytosis shown in a bone marrow sample. Therapeutic plasma exchange and intravenously administered high-dose corticosteroid for hemophagocytic lymphohistiocytosis and continuous renal replacement treatment for acute renal failure were initiated. Following 5-day high-dose corticosteroid administration, therapeutic plasma exchange, and continuous renal replacement treatment, his clinical status and kidney and liver functions improved, and vasoactive requirement and ferritin levels decreased. He was extubated on the seventh day. On the tenth day of hospitalization he had a seizure and was diagnosed as having septic encephalopathy. His immune functions were found to be normal. Although his medical condition improved continuously, he had left spontaneous pneumothorax on the 21st day of admission as a complication of necrotizing pneumonia. Since pneumothorax persisted, left upper lobectomy surgery was performed on the 30th day of hospitalization. In the pathological examination of the excised lung tissue, features of cytomegalovirus infection were observed. Ganciclovir treatment was started. Serological tests indicated that our patient had cytomegalovirus reactivation. Antiviral treatment was stopped after 17 days, w NA |
| مصطلحات الفهرس: | Medicine; Pediatry; Lymphohistiocytosis, CMV reactivation; Critically ill; Hemophagocytic lymphohistiocytosis; Multiple organ dysfunction; Pediatric; Sepsis; Hemophagocytic; Macrophage activation syndrome; Secondary hemophagocytic, Journal article, text/academic publication |
| URL: | Publisher version Koç University Institutional Repository |
| الإتاحة: | Open access content. Open access content |
| ملاحظة: | pdf English |
| أرقام أخرى: | T9K oai:libdigitalcollections.ku.edu.tr:IR/8163 1752-1947 Demirkol, Demet, Umay Kavgacı, Burcu Babaoğlu, Serhan Tanju, Sözmen B. Oflaz, and Suda Tekin. "Cytomegalovirus Reactivation in a Critically Ill Patient: a Case Report." Journal of Medical Case Reports. 12.1 (2018). IR00678.pdf Scopus; PubMed NA 1200730857 |
| المصدر المساهم: | KOC UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1200730857 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |