مورد إلكتروني
Late gadolinium uptake demonstrated with magnetic resonance in patients where automated PERFIT analysis of myocardial SPECT suggests irreversible perfusion defect
| العنوان: | Late gadolinium uptake demonstrated with magnetic resonance in patients where automated PERFIT analysis of myocardial SPECT suggests irreversible perfusion defect |
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| بيانات النشر: | Department of Clinical Physiology, County Hospital Ryhov, Jönköping, Sweden; Center for Medical Image Science and Visualization, CMIV, Linköping University Hospital, Linköping, Sweden Department of Clinical Physiology, County Hospital Ryhov, Jönköping, Sweden Department of Clinical Physiology, County Hospital Ryhov, Jönköping, Sweden Department of Clinical Physiology, County Hospital Ryhov, Jönköping, Sweden Department of Radiology, County Hospital Ryhov, Jönköping, Sweden Hospital Physics Unit, Dept. Of Oncology, County Hospital Ryhov, Jönköping, Sweden Center for Medical Image Science and Visualization, CMIV, Linköping, Sweden; Department of Clinical Physiology, Linköping University Hospital, Linköping, Sweden 2008 |
| تفاصيل مُضافة: | Rosendahl, Lene Blomstrand, Peter Ohlsson, Jan L. Björklund, Per-Gunnar Ahlander, Britt-Marie Starck, Sven-Ake Engvall, Jan E. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | BACKGROUND: Myocardial perfusion single photon emission computed tomography (MPS) is frequently used as the reference method for the determination of myocardial infarct size. PERFIT(R) is a software utilizing a three-dimensional gender specific, averaged heart model for the automatic evaluation of myocardial perfusion. The purpose of this study was to compare the perfusion defect size on MPS, assessed with PERFIT, with the hyperenhanced volume assessed by late gadolinium enhancement magnetic resonance imaging (LGE) and to relate their effect on the wall motion score index (WMSI) assessed with cine magnetic resonance imaging (cine-MRI) and echocardiography (echo). METHODS: LGE was performed in 40 patients where clinical MPS showed an irreversible uptake reduction suggesting a myocardial scar. Infarct volume, extent and major coronary supply were compared between MPS and LGE as well as the relationship between infarct size from both methods and WMSI. RESULTS: MPS showed a slightly larger infarct volume than LGE (MPS 29.6 +/- 23.2 ml, LGE 22.1 +/- 16.9 ml, p = 0.01), while no significant difference was found in infarct extent (MPS 11.7 +/- 9.4%, LGE 13.0 +/- 9.6%). The correlation coefficients between methods in respect to infarct size and infarct extent were 0.71 and 0.63 respectively. WMSI determined with cine-MRI correlated moderately with infarct volume and infarct extent (cine-MRI vs MPS volume r = 0.71, extent r = 0.71, cine-MRI vs LGE volume r = 0.62, extent r = 0.60). Similar results were achieved when wall motion was determined with echo. Both MPS and LGE showed the same major coronary supply to the infarct area in a majority of patients, Kappa = 0.84. CONCLUSION: MPS and LGE agree moderately in the determination of infarct size in both absolute and relative terms, although infarct volume is slightly larger with MPS. The correlation between WMSI and infarct size is moderate. |
| مصطلحات الفهرس: | Single Photon Emission Compute Tomography, Infarct Size, Late Gadolinium Enhancement, Perfusion Defect, Infarct Volume, Radiology, Nuclear Medicine and Medical Imaging, Radiologi och bildbehandling, Article in journal, info:eu-repo/semantics/article, text |
| DOI: | 10.1186.1471-2342-8-17 |
| URL: | BMC Medical Imaging, 1471-2342, 2008, 8 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | UPE oai:DiVA.org:oru-72075 0000-0001-5740-3538 doi:10.1186/1471-2342-8-17 PMID 19077270 Scopus 2-s2.0-63649087054 1233343965 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1233343965 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1186.1471-2342-8-17 |
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