مورد إلكتروني
Visualisation of zebrafish infection by GFP-labelled Vibrio anguillarum.
| العنوان: | Visualisation of zebrafish infection by GFP-labelled Vibrio anguillarum. |
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| بيانات النشر: | Molekylärbiologi (Teknisk-naturvetenskaplig fakultet) 2004 |
| تفاصيل مُضافة: | O'Toole, Ronan Von Hofsten, Jonas Rosqvist, Roland Olsson, Per-Erik Wolf-Watz, Hans |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Vibrio anguillarum is an invasive pathogen of fish causing a septicaemia called vibriosis. In this work, transparent zebrafish were immersed in water containing green fluorescent protein labelled V. anguillarum. The infection was visualised at the whole fish and single bacterium levels using microscopy. The gastrointestinal tract was the first site where the pathogen was detected. This enteric localisation occurred independently of the flagellum or motility. On the other hand, chemotactic motility was essential for association of the pathogen with the fish surface. In conclusion, the zebrafish infection model provides evidence that the intestine and skin represent sites of infection by V. anguillarum and suggests a host site where chemotaxis may function in virulence. |
| مصطلحات الفهرس: | Animals, Bacterial Adhesion, Chemotaxis, Flagella/physiology, Gastrointestinal Tract/microbiology/pathology, Genes; Reporter, Green Fluorescent Proteins, Luminescent Proteins/genetics/*metabolism, Movement, Skin/microbiology/pathology, Staining and Labeling/*methods, Vibrio/*pathogenicity/physiology, Vibrio Infections/*microbiology/pathology, Zebrafish/*microbiology, Article in journal, info:eu-repo/semantics/article, text |
| URL: | Microb Pathog, 0882-4010, 2004, 37:1, s. 41-6 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/restrictedAccess |
| ملاحظة: | English |
| أرقام أخرى: | UPE oai:DiVA.org:umu-16696 PMID 15194159 Scopus 2-s2.0-2942543194 1234500912 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1234500912 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |