Wastewater treatment from pharmaceutical substances with filamentous fungi

التفاصيل البيبلوغرافية
العنوان:	Wastewater treatment from pharmaceutical substances with filamentous fungi
بيانات النشر:	KTH, Industriell bioteknologi Riga Technical University Stockholm 2021
تفاصيل مُضافة:	Dalecka, Brigita
نوع الوثيقة:	Electronic Resource
مستخلص:	The ever-increasing concern about the widespread occurrence of pharmaceutical substances in the aquatic environment has been recognized as an emerging environmental issue as it can cause undesirable effects on the ecosystem and human health. The current wastewater treatment methods are not designed to treat municipal wastewater from the contamination of various pharmaceutical substances. As a result, pharmaceuticals can enter the environment and pose a threat to life forms. Therefore, it is important to enhance the classical wastewater treatment process in order to meet the challenges by advancing the technologies. Currently, the biological treatment method with filamentous fungi has been considered a promising, cost- effective, and environmentally friendly method for removing pharmaceutical substances from municipal wastewater. The thesis “Wastewater treatment from pharmaceutical substances with filamentous fungi” demonstrates the potential application of fungi in removing pharmaceutical substances and their expedience to incorporate into the classical municipal wastewater treatment process. The investigation focused on selecting suitable fungal strains that could adapt without adjusting physico-chemical parameters and compete with the microbial community in the municipal wastewater. Further, the thesis investigated whether fungal strains could reduce nutrients and pharmaceutical substances in lab-scale and pilot-scale setup and the mechanisms of pharmaceutical substance removal. The thesis consists of two main stages. In the first stage, the batch- scale experiments were carried out under laboratory conditions, finding out the most suitable fungal strains for the removal of pharmaceutical substances from wastewater. The results demonstrated that fungi compete with each other since higher removal efficiency was observed if the fungi were grown individually. Batch-scale experiments showed that Trametes versicolor a laboratory strain and Aspergillus luchuensis an e Promocijas darba “Mikroskopisko sēņu izmantošana sadzīves notekūdeņu attīrīšanā no farmaceitiski aktīvajām vielām” ietvaros ir veikta mikroskopisko sēņu izpēte un pilnveidota alternatīva metode notekūdeņu attīrīšanai no farmaceitiski aktīvajām vielām. Klasiskās notekūdeņu attīrīšanas metodes ne vienmēr var attīrīt sadzīves notekūdeņus no farmaceitiski aktīvo vielu piesārņojuma. Šī iemesla dēļ apkārtējā vidē var nonākt farmaceitiski aktīvās vielas un radīt apdraudējumu dzīvajiem organismiem. Lai novērstu farmaceitiski aktīvo vielu nokļūšanu apkārtējā vidē no sadzīves notekūdeņiem, nepieciešams meklēt jaunas un alternatīvas tehnoloģijas, lai uzlabotu gan jau esošās metodes, gan izstrādātu jaunas notekūdeņu attīrīšanas metodes. Kā viena no metodēm šī mērķa sasniegšanai var tikt izmantota bioloģiskā metode ar mikroskopiskajām sēnēm. Promocijas darba pētījums ir sadalīts divās galvenajās daļās. Pirmajā daļā tika veikti laboratorijas mēroga eksperimenti, lai noskaidrotu atbilstošākās mikroskopiskās sēnes notekūdeņu attīrīšanai no farmaceitiski aktīvajām vielām. Promocijas darba gaitā tika noskaidrots, ka mikroskopisko sēņu augstākā efektivitāte farmaceitisko vielu attīrīšanā no notekūdeņiem tika sasniegta, ja sēnes tiek izmantotas atsevišķi, nevis kombinētas savā starpā. Tika noskaidrots, ka Trametes veriocolor un Aspergillus luchuensis ir vispiemērotākās mikroskopiskās sēnes notekūdeņu attīrīšanai no farmaceitiskajām vielām. Tāpēc šīs mikroskopiskās sēnes tika izmantotas promocijas darba otrajā daļā. Promocijas darba otrajā daļā tika izstrādāts pilota mēroga bioreaktors. Šajā bioreaktorā tika pārbaudīta izvēlēto mikroskopisko sēņu efektivitāte farmaceitiski aktīvo vielu attīrīšanā no sadzīves notekūdeņiem. Darba gaitā tika pārbaudīta bioaugmentācija kā iespējamā metode, lai uzlabotu mik Den ständigt ökande oron om läkemedelsresters vida spridning i den akvatiska miljön är ett globalt erkänt växande problem, då dessa substanser orsakar oönskade effekter på människa och miljö. Dagens avloppsvattenreningsmetoder är inte designade för att rena vattnet från läkemedelsrester, vilket resulterar i att dessa substanser sprids och riskerar orsaka skada. På grund av detta är det viktigt att förbättra den konventionella reningsprocessen för att möta framtidens krav på läkemedelsrening. En lovande teknik för att åstadkomma denna förbättring är biologisk rening med hjälp av filamentösa mikrosvampar, vilken visat sig vara både kostnadseffektiv och miljövänlig. Syftet med denna avhandling var således att undersöka möjligheten att tillämpa mikrosvampar för att rena vatten från läkemedelsrester, men också hur väl en sådan lösning skulle kunna passa in i ett konventionellt reningsverk. Arbetet fokuserade på att hitta lämpliga stammar av mikrosvampar som kunde anpassa sig till miljön i en konventionell avloppsvattenreningsprocess utan att konkurrera med den aktiva mikrobiologiska floran, eller att behöva förändra rådande fysikalisk-kemiska parametrar. Vidare undersöktes hur väl lämpliga kandidater av mikrosvampar reducerade näringsämnen och läkemedelsrester, samt dess mekanismer, både i labbskale- och pilotskaleförsök. Avhandlingen består av två delar i vilken den första behandlar batch- experiment i labbskala som genomfördes i labbmiljö där lämpliga stammar av mikrosvampar utvärderades efter dess förmåga att rena vatten från läkemedelsrester. Resultaten visade att svamparna konkurrerar med varandra då högre reduktion observerades i de fall svamparna odlades individuellt. Två lovande kandidater att använda i en icke-steril miljö utan pH-justering var Trametes versicolor, en laboratoriestamm, samt Aspergillus luchuensis, ett isolat från ett kommunalt avloppsreningsverk. Dessa två kandida QC 2021-03-01
مصطلحات الفهرس:	Filamentous fungi, municipal wastewater, pharmaceutical substances, fungal fluidized bed pelleted bioreactor, nutrients, diclofenac, ketoprofen, Trametes versicolor, Aspergillus luchuensis, Filamentösa svampar, kommunalt avloppsvatten, läkemedelsrester, bioreaktor, näringsämnen, diklofenak, Mikroskopiskās sēnes, sadzīves notekūdeņi, farmaceitiskās vielas, mikroskopisko sēņu bioreaktors, diklofenaks, ketoprofens, Water Engineering, Vattenteknik, Doctoral thesis, comprehensive summary, info:eu-repo/semantics/doctoralThesis, text
URL:	http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-291098 TRITA-CBH-FOU ; 2021:5
الإتاحة:	Open access content. Open access content info:eu-repo/semantics/openAccess
ملاحظة:	application/pdf English
أرقام أخرى:	UPE oai:DiVA.org:kth-291098 0000-0001-9304-881x urn:isbn:978-91-7873-798-7 1280648512
المصدر المساهم:	UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative.
رقم الأكسشن:	edsoai.on1280648512
قاعدة البيانات:	OAIster

الوصف
الوصف غير متاح.