مورد إلكتروني
Neuronize v2: Bridging the Gap Between Existing Proprietary Tools to Optimize Neuroscientific Workflows
| العنوان: | Neuronize v2: Bridging the Gap Between Existing Proprietary Tools to Optimize Neuroscientific Workflows |
|---|---|
| بيانات النشر: | Frontiers Media 2020-10-06 |
| تفاصيل مُضافة: | Ministerio de Ciencia, Innovación y Universidades (España) Cajal Blue Brain École Polytechnique Fédérale de Lausanne European Commission Velasco, Iván Toharia, P. Benavides-Piccione, Ruth Fernaud-Espinosa, Isabel Brito, J.P. Mata, S. DeFelipe, Javier Pastor, L. Bayona, S. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Knowledge about neuron morphology is key to understanding brain structure and function. There are a variety of software tools that are used to segment and trace the neuron morphology. However, these tools usually utilize proprietary formats. This causes interoperability problems since the information extracted with one tool cannot be used in other tools. This article aims to improve neuronal reconstruction workflows by facilitating the interoperability between two of the most commonly used software tools—Neurolucida (NL) and Imaris (Filament Tracer). The new functionality has been included in an existing tool—Neuronize—giving rise to its second version. Neuronize v2 makes it possible to automatically use the data extracted with Imaris Filament Tracer to generate a tracing with dendritic spine information that can be read directly by NL. It also includes some other new features, such as the ability to unify and/or correct inaccurately-formed meshes (i.e., dendritic spines) and to calculate new metrics. This tool greatly facilitates the process of neuronal reconstruction, bridging the gap between existing proprietary tools to optimize neuroscientific workflows. |
| مصطلحات الفهرس: | neuron morphology, interoperability, neuronal tracing, spine meshes, data sharing, 3D morphological reconstruction, pyramidal structure, artículo |
| URL: | Publisher's version Sí info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/TIN2017-83132-C2 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-094307-B-I00 info:eu-repo/grantAgreement/EC/H2020/785907 info:eu-repo/grantAgreement/EC/H2020/945539 |
| الإتاحة: | Open access content. Open access content https://creativecommons.org/licenses/by/4.0 openAccess |
| أرقام أخرى: | CTK oai:digital.csic.es:10261/227614 Frontiers in neuroanatomy 14 (2020) 10.3389/fnana.2020.585793 1286561581 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1286561581 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |