مورد إلكتروني
Simultaneous ThermoBrachytherapy: Electromagnetic Simulation Methods for Fast and Accurate Adaptive Treatment Planning
| العنوان: | Simultaneous ThermoBrachytherapy: Electromagnetic Simulation Methods for Fast and Accurate Adaptive Treatment Planning |
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| بيانات النشر: | 2022 |
| تفاصيل مُضافة: | Androulakis, Ioannis (author) Mestrom, Rob M.C. (author) Christianen, Miranda E.M.C. (author) Kolkman‐deurloo, Inger Karine K. (author) van Rhoon, G.C. (author) |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The combination of interstitial hyperthermia treatment (IHT) with high dose rate brachytherapy (HDR‐BT) can improve clinical outcomes since it highly enhances the efficiency of cell kill, especially when applied simultaneously. Therefore, we have developed the ThermoBrachy applicators. To effectively apply optimal targeted IHT, treatment planning is considered essential. However, treatment planning in IHT is rarely applied as it is regarded as difficult to accurately calculate the deposited energy in the tissue in a short enough time for clinical practice. In this study, we investigated various time‐efficient methods for fast computation of the electromagnetic (EM) energy deposition resulting from the ThermoBrachy applicators. Initially, we investigated the use of an electro‐quasistatic solver. Next, we extended our investigation to the application of geometric simplifications. Furthermore, we investigated the validity of the superpositioning principle, which can enable adaptive treatment plan optimization without the need for continuous recomputation of the EM field. Finally, we evaluated the accuracy of the methods by comparing them to the golden standard Finite‐Difference Time‐Domain calculation method using gamma‐index analysis. The simplifications considerably reduced the computation time needed, improving from >12 h to a few seconds. All investigated methods showed excellent agreement with the golden standard by showing a >99% passing rate with 1%/0.5 mm Dose Difference and Distance‐to‐Agreement criteria. These results allow the proposed electromagnetic simulation method to be used for fast and accurate adaptive treatment planning. RST/Applied Radiation & Isotopes |
| مصطلحات الفهرس: | Automated treatment planning, Capacitive heating, Electromagnetic simulations, Finite‐difference time‐domain, Gamma index analysis, High dose rate brachytherapy, Interstitial hyperthermia, Quasistatic simulations, ThermoBrachytherapy, Treatment plan optimization, journal article |
| DOI: | 10.3390.s22041328 |
| URL: | Sensors--1424-8220--86a08093-a97e-45a0-a351-caecadb51153 |
| الإتاحة: | Open access content. Open access content © 2022 Ioannis Androulakis, Rob M.C. Mestrom, Miranda E.M.C. Christianen, Inger Karine K. Kolkman‐deurloo, G.C. van Rhoon |
| ملاحظة: | English |
| أرقام أخرى: | NLTUD oai:tudelft.nl:uuid:6e2c052c-ed7d-4969-93a1-79297f68d808 doi:10.3390/s22041328 1310080885 |
| المصدر المساهم: | DELFT UNIV OF TECHNOL From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1310080885 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.3390.s22041328 |
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