مورد إلكتروني
CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples
| العنوان: | CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples |
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| بيانات النشر: | Linköpings universitet, Medicinska fakulteten Linköpings universitet, Avdelningen för cellbiologi Linköpings universitet, Avdelningen för inflammation och infektion Linköpings universitet, Institutionen för biomedicinska och kliniska vetenskaper Region Östergötland, Klinisk mikrobiologi Reg Jonkoping Cty, Dept Lab Med Jonkoping Reg Jonkoping Cty, Dept Lab Med Jonkoping Reg Jonkoping Cty, Dept Infect Dis Reg Jonkoping Cty, Dept Lab Med Jonkoping Reg Kronoberg, Sweden Orebro Univ, Sweden Reg Jonkoping Cty, Dept Lab Med Jonkoping Springer 2022 |
| تفاصيل مُضافة: | Haglund, Sofie Lager, Malin Gyllemark, Paula Andersson, Gärda Ekelund, Oskar Sundqvist, Martin Jonsson Henningsson, Anna |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The chemokine CXCL13 is used as complement to serology in the diagnostics of Lyme neuroborreliosis (LNB). We evaluated and compared the semi-quantitative, cassette-based ReaScan CXCL13 assay with the quantitative recomBead CXCL13 assay using a collection of 209 cerebrospinal fluid samples. The categorical agreement between results interpreted as negative, grey zone, and positive by the two methods was 87%. The diagnostic sensitivity was higher using the recomBead assay, whereas specificity was higher using ReaScan. Few manual steps, and a short turn-around time with no batching of samples makes the ReaScan CXCL13 assay an attractive complement to serology in the diagnostics of LNB. Funding Agencies|European Union through the European Regional Development FundEuropean Commission; Interreg North Sea Region Programme [J-No: 38-2-7-19] |
| مصطلحات الفهرس: | Lyme neuroborreliosis; Diagnostics; CXCL13; ReaScan; recomBead, Microbiology in the medical area, Mikrobiologi inom det medicinska området, Article in journal, info:eu-repo/semantics/article, text |
| DOI: | 10.1007.s10096-021-04350-y |
| URL: | European Journal of Clinical Microbiology and Infectious Diseases, 0934-9723, 2022, 41:1, s. 175-179 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | UPE oai:DiVA.org:liu-180499 0000-0002-9315-8901 doi:10.1007/s10096-021-04350-y PMID 34626256 ISI:000705823200001 1312835625 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1312835625 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1007.s10096-021-04350-y |
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