مورد إلكتروني
The origins and genomic diversity of American Civil War Era smallpox vaccine strains.
| العنوان: | The origins and genomic diversity of American Civil War Era smallpox vaccine strains. |
|---|---|
| المؤلفون: | Duggan, AT, Klunk, J, Porter, AF, Dhody, AN, Hicks, R, Smith, GL, Humphreys, M, McCollum, AM, Davidson, WB, Wilkins, K, Li, Y, Burke, A, Polasky, H, Flanders, L, Poinar, D, Raphenya, AR, Lau, TTY, Alcock, B, McArthur, AG, Golding, GB, Holmes, EC, Poinar, HN |
| بيانات النشر: | BioMed Central 2020-07-20 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination. Prior to the twentieth century, the method, source and origin of smallpox vaccinations remained unstandardised and opaque. We reconstruct and analyse viral vaccine genomes associated with smallpox vaccination from historical artefacts. Significantly, we recover viral molecules through non-destructive sampling of historical materials lacking signs of biological residues. We use the authenticated ancient genomes to reveal the evolutionary relationships of smallpox vaccination viruses within the poxviruses as a whole. |
| مصطلحات الفهرس: | Journal Article |
| URL: | |
| الإتاحة: | Open access content. Open access content CC BY https://creativecommons.org/licenses/by/4.0 |
| أرقام أخرى: | UMV oai:jupiter.its.unimelb.edu.au:11343/277714 Duggan, A. T., Klunk, J., Porter, A. F., Dhody, A. N., Hicks, R., Smith, G. L., Humphreys, M., McCollum, A. M., Davidson, W. B., Wilkins, K., Li, Y., Burke, A., Polasky, H., Flanders, L., Poinar, D., Raphenya, A. R., Lau, T. T. Y., Alcock, B., McArthur, A. G. ,... Poinar, H. N. (2020). The origins and genomic diversity of American Civil War Era smallpox vaccine strains.. Genome Biology, 21 (1), pp.175-175. https://doi.org/10.1186/s13059-020-02079-z. 10.1186/s13059-020-02079-z 1474-760X 1474-7596 1315693322 |
| المصدر المساهم: | UNIV OF MELBOURNE From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1315693322 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |