مورد إلكتروني
Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria:a retrospective study
| العنوان: | Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria:a retrospective study |
|---|---|
| المصدر: | Filippi , M , Preziosa , P , Meani , A , Ciccarelli , O , Mesaros , S , Rovira , A , Frederiksen , J , Enzinger , C , Barkhof , F , Gasperini , C , Brownlee , W , Drulovic , J , Montalban , X , Cramer , S P , Pichler , A , Hagens , M , Ruggieri , S , Martinelli , V , Miszkiel , K , Tintorè , M , Comi , G , Dekker , I , Uitdehaag , B , Dujmovic-Basuroski , I & Rocca , M A 2018 , ' Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria : a retrospective study ' , Lancet Neurology , vol. 17 , no. 2 , pp. 133-142 . |
| بيانات النشر: | 2018 |
| تفاصيل مُضافة: | Filippi, Massimo Preziosa, Paolo Meani, Alessandro Ciccarelli, Olga Mesaros, Sarlota Rovira, Alex Frederiksen, Jette Enzinger, Christian Barkhof, Frederik Gasperini, Claudio Brownlee, Wallace Drulovic, Jelena Montalban, Xavier Cramer, Stig P Pichler, Alexander Hagens, Marloes Ruggieri, Serena Martinelli, Vittorio Miszkiel, Katherine Tintorè, Mar Comi, Giancarlo Dekker, Iris Uitdehaag, Bernard Dujmovic-Basuroski, Irena Rocca, Maria A |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | BACKGROUND: In 2016, the Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) network proposed modifications to the MRI criteria to define dissemination in space (DIS) and time (DIT) for the diagnosis of multiple sclerosis in patients with clinically isolated syndrome (CIS). Changes to the DIS definition included removal of the distinction between symptomatic and asymptomatic lesions, increasing the number of lesions needed to define periventricular involvement to three, combining cortical and juxtacortical lesions, and inclusion of optic nerve evaluation. For DIT, removal of the distinction between symptomatic and asymptomatic lesions was suggested. We compared the performance of the 2010 McDonald and 2016 MAGNIMS criteria for multiple sclerosis diagnosis in a large multicentre cohort of patients with CIS to provide evidence to guide revisions of multiple sclerosis diagnostic criteria.METHODS: Brain and spinal cord MRI and optic nerve assessments from patients with typical CIS suggestive of multiple sclerosis done less than 3 months from clinical onset in eight European multiple sclerosis centres were included in this retrospective study. Eligible patients were 16-60 years, and had a first CIS suggestive of CNS demyelination and typical of relapsing-remitting multiple sclerosis, a complete neurological examination, a baseline brain and spinal cord MRI scan obtained less than 3 months from clinical onset, and a follow-up brain scan obtained less than 12 months from CIS onset. We recorded occurrence of a second clinical attack (clinically definite multiple sclerosis) at months 36 and 60. We evaluated MRI criteria performance for DIS, DIT, and DIS plus DIT with a time-dependent receiver operating characteristic curve analysis.FINDINGS: Between June 16, 1995, and Jan 27, 2017, 571 patients with CIS were screened, of whom 368 met all study inclusion criteria. At the last evaluation (median 50·0 months [IQR 27·0-78·4]), 189 (51%) of 368 patients de |
| مصطلحات الفهرس: | Adult, Brain/diagnostic imaging, Brain Stem/diagnostic imaging, Cerebellar Diseases/diagnostic imaging, Cerebral Ventricles/diagnostic imaging, Cohort Studies, Demyelinating Diseases/diagnostic imaging, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Magnetic Resonance Imaging, Male, Multiple Sclerosis/diagnostic imaging, Neurologic Examination, Optic Nerve/diagnostic imaging, Optic Neuritis/diagnostic imaging, Spinal Cord/diagnostic imaging, article |
| URL: | |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/closedAccess |
| ملاحظة: | English |
| أرقام أخرى: | DAV oai:pure.atira.dk:publications/a4adc592-1f6e-4350-b692-429fb3d714c4 1322724045 |
| المصدر المساهم: | UNIV OF COPENHAGEN From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1322724045 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |