مورد إلكتروني
Theragnostic application of nanoparticle and CRISPR against food-borne multi-drug resistant pathogens
| العنوان: | Theragnostic application of nanoparticle and CRISPR against food-borne multi-drug resistant pathogens |
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| بيانات النشر: | Uppsala universitet, Materialteori Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Assam Agr Univ, Dept Agr Biotechnol, DBT NECAB, Jorhat 785013, Assam, India. Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City, Mexico. Univ Southern Denmark, Mads Clausen Inst, NanoSYD, Alsion 2, DK-6400 Sonderborg, Denmark. Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India. Elsevier BV 2022 |
| تفاصيل مُضافة: | Bhattacharjee, Rahul Nandi, Aditya Mitra, Priya Saha, Koustav Patel, Paritosh Jha, Ealisha Panda, Pritam Kumar Singh, Sushil Kumar Dutt, Ateet Mishra, Yogendra Kumar Verma, Suresh K. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Foodborne infection is one of the leading sources of infections spreading across the world. Foodborne pathogens are recognized as multidrug-resistant (MDR) pathogens posing a significant problem in the food industry and healthy consumers resulting in enhanced economic burden, and nosocomial infections. The continued search for enhanced microbial detection tools has piqued the interest of the CRISPR-Cas system and Nanoparticles. CRISPRCas system is present in the bacterial genome of some prokaryotes and is repurposed as a theragnostic tool against MDR pathogens. Nanoparticles and composites have also emerged as an efficient tool in theragnostic applications against MDR pathogens. The diagnostic limitations of the CRISPR-Cas system are believed to be overcome by a synergistic combination of the nanoparticles system and CRISPR-Cas using nanoparticles as vehicles. In this review, we have discussed the diagnostic application of CRISPR-Cas technologies along with their potential usage in applications like phage resistance, phage vaccination, strain typing, genome editing, and antimicrobial. we have also elucidated the antimicrobial and detection role of nanoparticles against foodborne MDR pathogens. Moreover, the novel combinatorial approach of CRISPR-Cas and nanoparticles for their synergistic effects in pathogen clearance and drug delivery vehicles has also been discussed. |
| مصطلحات الفهرس: | Antimicrobial activity, Diagnosis, CRISPR-Cas system, Nanoparticle and MDR food-Borne-pathogens, Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy), Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci), Article in journal, info:eu-repo/semantics/article, text |
| DOI: | 10.1016.j.mtbio.2022.100291 |
| URL: | 2022, 15 MATERIALS TODAY BIO, 2590-0064, 2022, 15 |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| أرقام أخرى: | UPE oai:DiVA.org:uu-480278 0000-0003-4879-2302 0000-0003-1029-9766 doi:10.1016/j.mtbio.2022.100291 PMID 35711292 ISI:000813433100004 1337541452 |
| المصدر المساهم: | UPPSALA UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1337541452 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1016.j.mtbio.2022.100291 |
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