مورد إلكتروني
Control of iodine deficiency using iodination of water in a goitre endemic area.
| العنوان: | Control of iodine deficiency using iodination of water in a goitre endemic area. |
|---|---|
| المصدر: | International journal of food sciences and nutrition, 48 (2 |
| بيانات النشر: | 1997-03 |
| تفاصيل مُضافة: | Elnagar, B Eltom, M Karlsson, F A Bourdoux, Pierre Gebre-Medhin, M |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Salt iodination is the method of choice for prevention of iodine deficiency in most parts of the world. However, establishment of such a program frequently involves considerable changes in the marketing and distribution patterns and requires years to achieve. This study was conducted to evaluate the efficiency of using well-defined water sources containing iodine-saturated silicon matrices for providing adequate iodine supply to an iodine deficient population in Kordofan State, Western Sudan. A system of water iodination using silicon matrices containing 30% sodium iodide placed in polyethylene baskets was used in four villages using either traditional wells or hand pumps. Before and every 6 months after iodination of water, urine and blood samples were obtained for determination of iodine and thyroid-related hormones, respectively. Goitre assessment on the village populations were performed at the start and 2 years later. Improvements in iodine status were recorded in all the study villages. The water iodine concentrations increased and a higher iodine content was observed in the hand pumps compared to the traditional wells. The median urinary iodine concentrations increased significantly, from 0.19, 0.20, 0.19, 0.11 to 1.20, 1.10, 0.37, 0.30 mumol/l in the four villages, respectively. The percentages of subjects with serum TSH above 4 mU/l were decreased from more than 30% before iodination to less than 15% at 2 years after iodine supply and the mean serum thyroxine hormone values rose. The rates of goitre decreased from 69% to less than 25%. The study shows that this system is effective, cheap, safe and practically applicable under conditions prevailing in rural areas in developing countries with iodine deficiency. Journal Article Research Support, Non-U.S. Gov't SCOPUS: ar.j info:eu-repo/semantics/published |
| مصطلحات الفهرس: | Epidémiologie, Chimie pharmaceutique, Endocrinologie, Obstétrique, Sciences bio-médicales et agricoles, Female, Follow-Up Studies, Goiter, Endemic -- drug therapy -- epidemiology -- metabolism, Humans, Iodine -- deficiency -- urine, Male, Prevalence, Rural Health, Sodium Iodide -- administration & dosage -- therapeutic use, Sudan -- epidemiology, Thyroid Hormones -- blood, Thyrotropin -- blood, Water Supply, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article |
| URL: | |
| الإتاحة: | Open access content. Open access content |
| ملاحظة: | No full-text files English |
| أرقام أخرى: | EQY oai:dipot.ulb.ac.be:2013/123293 uri/info:pmid/9135775 uri/info:scp/0030612992 1363734250 |
| المصدر المساهم: | UNIVERSITE LIBRE DE BRUXELLES From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1363734250 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |