مورد إلكتروني
Chromosome evolution of MMU16 and RNO11: conserved synteny associated with gene order rearrangements explicable by intrachromosomal recombinations and neocentromere emergence
| العنوان: | Chromosome evolution of MMU16 and RNO11: conserved synteny associated with gene order rearrangements explicable by intrachromosomal recombinations and neocentromere emergence |
|---|---|
| المصدر: | Cytogenetic and Genome Research |
| بيانات النشر: | 2005 |
| تفاصيل مُضافة: | Szpirer, Claude Riviere, Michèle Van Vooren, Pascale Moisan, M. P. Haller, O. Szpirer, Josiane |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Comparative mapping between the rat and mouse genomes has shown that some chromosomes are entirely or almost entirely conserved with respect to gene content. Such is the case of rat chromosome 11 (RNO11) and mouse chromosome 16 (MMU16). We determined to what extent such an extensive conservation of synteny is associated with a conserved gene order. Therefore, we regionally localized several genes on RNO11. The comparison of the gene map of RNO11 and MMU16 unambiguously shows that the gene order has not been conserved in the Murinae lineage, thereby implying the occurrence of intrachromosomal evolutionary rearrangements. The transition from one chromosome configuration to the other one can be explained either by two intrachromosomal recombinations or by a single intrachromosomal recombination accompanied by neocentromere emergence. Comparative Study Journal Article Research Support, Non-U.S. Gov't info:eu-repo/semantics/published |
| مصطلحات الفهرس: | Biologie moléculaire, Génétique, cytogénétique, Animals, Chromosome Mapping -- methods, Chromosomes, Mammalian -- genetics, Conserved Sequence -- genetics, Evolution, Molecular, Gene Order -- genetics, Gene Rearrangement -- genetics, Genome, Mice, Rats, Synteny -- genetics, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article |
| URL: | |
| الإتاحة: | Open access content. Open access content |
| ملاحظة: | No full-text files English |
| أرقام أخرى: | EQY oai:dipot.ulb.ac.be:2013/17865 uri/info:doi/10.1159/000081526 uri/info:pii/CGR2005108004322 uri/info:pmid/15627752 uri/info:scp/11444257435 local/cs-0007 1363760208 |
| المصدر المساهم: | UNIVERSITE LIBRE DE BRUXELLES From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1363760208 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |