مورد إلكتروني
PSA response to lenalidomide therapy in a pre-treated patient with metastatic prostate cancer refractory to hormones and chemotherapy: a case report
| العنوان: | PSA response to lenalidomide therapy in a pre-treated patient with metastatic prostate cancer refractory to hormones and chemotherapy: a case report |
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| بيانات النشر: | S. Karger AG, Basel 2012-04-18 |
| تفاصيل مُضافة: | Universidad de Alicante. Departamento de Biotecnología Gasent Blesa, Joan Manel Peris Godoy, Miguel Fonfría Esparcia, María Blasco Mollá, Sara Mancheño Magán, Balbino Sempere Ortells, José Miguel Sánchez, José Luis |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Hormone-resistant prostate cancer (HRPC) occurs when prostate cancer is no longer responsive to hormone therapy. Treatment options are limited, and there is a clear necessity for therapies that improve outcome. Preclinical and clinical evidence supports the role of the immunomodulatory agent lenalidomide in HRPC. In this paper, we report that lenalidomide showed antitumoral activity in a patient with HRPC and bone metastases pre-treated with chemotherapy, decreased the PSA level and improved the patient’s health status for the first 5 months. It is important to emphasize that it was not associated with hematologic toxicity. |
| مصطلحات الفهرس: | Hormone-resistant prostate cancer, Prostate serum antigen, Lenalidomide, info:eu-repo/semantics/article |
| URL: | |
| الإتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess © 2012 S. Karger AG, Basel. This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only. |
| أرقام أخرى: | ESALI oai:rua.ua.es:10045/34301 Case Reports in Oncology. 2012, 5: 181-186. doi:10.1159/000336481 1662-6575 10.1159/000336481 1364507811 |
| المصدر المساهم: | UNIV DE ALICANTE From OAIster®, provided by the OCLC Cooperative. |
| رقم الأكسشن: | edsoai.on1364507811 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |